Lopez-de-Andrés A, Jiménez-García R, Jiménez-Trujillo I, Hernández-Barrera V, de Miguel-Yanes J M, Méndez-Bailón M, Perez-Farinos N, de Miguel-Diez J, Salinero-Fort M Á, Carrasco-Garrido P
Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcón, Comunidad de Madrid, Spain.
Medicine Department, Hospital Gregorio Marañon, Madrid, Comunidad de Madrid, Spain.
Osteoporos Int. 2016 Feb;27(2):605-16. doi: 10.1007/s00198-015-3305-9. Epub 2015 Aug 29.
Hip fracture is a serious public health problem. We used Spanish hospital discharge data to examine trends in 2004-2013 in the incidence of hip fracture among elderly patients. We found that hip fracture incidence is higher in subjects with than without diabetes and is much higher among women than men.
This study aimed to describe trends in the incidence of hip fracture hospitalizations, use of surgical procedures, and hospital outcomes among elderly patients with and without type 2 diabetes mellitus (T2DM) in Spain, 2004-2013.
We selected all patients with a discharge primary diagnosis of hip fracture using the Spanish national hospital discharge database. Discharges were grouped by diabetes status: Incidences were calculated overall and stratified by diabetes status and year. We analyzed surgical procedures, length of hospital stay (LOHS), and in-hospital mortality (IHM). Multivariate analysis was adjusted by age, year, comorbidity, and in-hospital complications (IHC).
From 2004 to 2013, 432,760 discharges with hip fracture were identified (21.3 % suffered T2DM). Incidence among diabetic men and women increased until year 2010 and then remained stable. Diabetic women have three times higher incidence than diabetic men. Incidences and IHC were higher among patients with diabetes beside sex. The proportion of patients that underwent internal fixation increased for all groups of patients and the arthroplasty repair decreased. After multivariate analysis, IHM has improved over the study period for all patients. Suffering diabetes was associated to higher IHM in women (odds ratio (OR) 1.12; 95 % confidence interval (CI) 1.07-1.17).
Hip fracture incidence is higher in subjects with than without diabetes and is much higher among women than men. In diabetic patients, incidence rates increased initially but have leveled from 2010 onwards. For all groups, the use of internal fixation has increased overtime and IHM and LOHS have decreased from 2004 to 2013.
髋部骨折是一个严重的公共卫生问题。我们利用西班牙医院出院数据研究了2004年至2013年老年患者髋部骨折发病率的趋势。我们发现,患有糖尿病的受试者的髋部骨折发病率高于未患糖尿病的受试者,且女性的发病率远高于男性。
本研究旨在描述2004年至2013年西班牙患有和未患有2型糖尿病(T2DM)的老年患者髋部骨折住院发病率、手术程序使用情况及医院治疗结果的趋势。
我们使用西班牙国家医院出院数据库选取了所有出院主要诊断为髋部骨折的患者。出院情况按糖尿病状态分组:计算总体发病率,并按糖尿病状态和年份分层。我们分析了手术程序、住院时间(LOHS)和院内死亡率(IHM)。多变量分析根据年龄、年份、合并症和院内并发症(IHC)进行了调整。
2004年至2013年,共确定432,760例髋部骨折出院病例(21.3%患有T2DM)。糖尿病男性和女性的发病率在2010年之前上升,之后保持稳定。糖尿病女性的发病率是糖尿病男性的三倍。除性别外,糖尿病患者的发病率和IHC更高。所有患者组接受内固定的患者比例增加,而关节成形术修复比例下降。多变量分析后,所有患者在研究期间的IHM有所改善。患糖尿病与女性较高的IHM相关(比值比(OR)1.12;95%置信区间(CI)1.07 - 1.17)。
患有糖尿病的受试者的髋部骨折发病率高于未患糖尿病的受试者,且女性的发病率远高于男性。在糖尿病患者中,发病率最初上升,但从2010年起趋于平稳。对于所有组,内固定的使用随时间增加,且2004年至2013年IHM和LOHS有所下降。