Özdemir-van Brunschot Denise M D, van Laarhoven Cees J H M, van der Jagt Michel F P, Hoitsma Andries J, Warlé Michiel C
Division of Vascular and Transplant Surgery, Department of Surgery, Radboud University Nijmegen Medical Center, Geert Grooteplein-Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.
World J Surg. 2016 Feb;40(2):471-8. doi: 10.1007/s00268-015-3232-0.
The lengths of right renal veins are shorter when compared to their left counterparts. Since the implantation of kidneys with short renal veins is considered more challenging, many surgeons prefer left kidneys for transplantation. Therefore, our hypothesis is that the implantation of right kidneys from living and deceased donors is associated with more technical graft failures as compared to left kidneys.
Two consecutive cohorts of adult renal allograft recipients of living (n = 4.372) and deceased (n = 5.346) donor kidneys between January 1, 2000 and January 1, 2013 were analyzed. Data were obtained from the prospectively maintained electronic database of the Dutch Organ Transplant Registry. Technical graft failure was defined as failure of the renal allograft within 10 days after renal transplantation without signs of acute rejection.
In the living donor kidney transplantation cohort, the implantation of right donor kidneys was associated with a higher incidence of technical graft failure (multivariate analysis p = 0.03). For recipients of deceased donor kidneys, the implantation of right kidneys was not significantly associated with technique-related graft failure (multivariate analysis p = 0.16).
Our data show that the implantation of right kidneys from living donors is associated with a higher incidence of technique-related graft failure as compared to left kidneys.
与左肾静脉相比，右肾静脉的长度较短。由于肾静脉短的肾脏移植被认为更具挑战性，许多外科医生更倾向于选择左肾进行移植。因此，我们的假设是，与左肾相比，来自活体和已故供体的右肾移植与更多的技术相关移植失败有关。
分析了2000年1月1日至2013年1月1日期间连续的两组成年肾移植受者队列，分别为活体供肾（n = 4372）和已故供肾（n = 5346）。数据来自荷兰器官移植登记处前瞻性维护的电子数据库。技术相关移植失败定义为肾移植后10天内肾移植失败且无急性排斥反应迹象。
在活体供肾移植队列中，右供肾移植与技术相关移植失败的发生率较高相关（多变量分析p = 0.03）。对于已故供肾的受者，右肾移植与技术相关移植失败无显著相关性（多变量分析p = 0.16）。
我们的数据表明，与左肾相比，活体供体右肾移植与技术相关移植失败的发生率较高相关。
