German Center for Neurodegenerative Diseases (DZNE), Stockumer Straße 12, 58453 Witten, Germany; School of Nursing Science, Witten/Herdecke University, Stockumer Straße 12, 58453 Witten, Germany.
German Center for Neurodegenerative Diseases (DZNE), Stockumer Straße 12, 58453 Witten, Germany; School of Nursing Science, Witten/Herdecke University, Stockumer Straße 12, 58453 Witten, Germany.
J Clin Epidemiol. 2016 Feb;70:233-45. doi: 10.1016/j.jclinepi.2015.08.002. Epub 2015 Aug 28.
For people with dementia, the concept of quality of life (Qol) reflects the disease's impact on the whole person. Thus, Qol is an increasingly used outcome measure in dementia research. This systematic review was performed to identify available dementia-specific Qol measurements and to assess the quality of linguistic validations and reliability studies of these measurements (PROSPERO 2013: CRD42014008725).
The MEDLINE, CINAHL, EMBASE, PsycINFO, and Cochrane Methodology Register databases were systematically searched without any date restrictions. Forward and backward citation tracking were performed on the basis of selected articles.
A total of 70 articles addressing 19 dementia-specific Qol measurements were identified; nine measurements were adapted to nonorigin countries. The quality of the linguistic validations varied from insufficient to good. Internal consistency was the most frequently tested reliability property. Most of the reliability studies lacked internal validity.
Qol measurements for dementia are insufficiently linguistic validated and not well tested for reliability. None of the identified measurements can be recommended without further research. The application of international guidelines and quality criteria is strongly recommended for the performance of linguistic validations and reliability studies of dementia-specific Qol measurements.
对于痴呆患者，生活质量（Qol）的概念反映了疾病对整个人的影响。因此，Qol 是痴呆症研究中越来越常用的结果衡量标准。本系统评价旨在确定可用的痴呆症特异性 Qol 测量方法，并评估这些测量方法的语言验证和可靠性研究的质量（PROSPERO 2013：CRD42014008725）。
系统地检索了 MEDLINE、CINAHL、EMBASE、PsycINFO 和 Cochrane 方法学登记册数据库，没有任何日期限制。根据选定的文章进行了向前和向后引用追踪。
共确定了 70 篇涉及 19 种痴呆症特异性 Qol 测量方法的文章；其中 9 种测量方法适用于非原始国家。语言验证的质量从不足到良好不等。内部一致性是最常测试的可靠性属性。大多数可靠性研究缺乏内部有效性。
痴呆症的 Qol 测量方法在语言验证方面不够充分，在可靠性方面也没有经过充分测试。在没有进一步研究的情况下，不能推荐使用任何已确定的测量方法。强烈建议在进行痴呆症特异性 Qol 测量的语言验证和可靠性研究时应用国际指南和质量标准。
