Hoben Matthias, Chamberlain Stephanie A, O'Rourke Hannah M, Elliott Brittany, Shrestha Shovana, Devkota Rashmi, Thorne Trina, Lam Jenny, Banerjee Sube, Hughes Laura, Estabrooks Carole A
Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
BMJ Open. 2021 Feb 5;11(2):e041318. doi: 10.1136/bmjopen-2020-041318.
Dementia is a public health issue and a major risk factor for poor quality of life among older adults. In the absence of a cure, enhancing health-related quality of life (HRQoL) of people with dementia is the primary goal of care. Robust measurement of HRQoL is a prerequisite to effective improvement. The DEMQOL suite of instruments is considered among the best available to measure HRQoL in people with dementia; however, no review has systematically and comprehensively examined the use of the DEMQOL in research and summarised evidence to determine its feasibility, acceptability and appropriateness for use in research and practice.
We will systematically search 12 electronic databases and reference lists of all included studies. We will include systematically conducted reviews, as well as, quantitative and qualitative research studies that report on the development, validation or use in research studies of any of the DEMQOL instruments. Two reviewers will independently screen all studies for eligibility, and assess the quality of each included study using one of four validated checklists appropriate for different study designs. Discrepancies at all stages of the review will be resolved by consensus. We will use descriptive statistics (frequencies, proportions, ranges), content analysis of narrative data and vote counting (for the measures of association) to summarise the data elements. Using narrative synthesis, we will summarise what is known about the development, validation, feasibility, acceptability, appropriateness and use of the DEMQOL. Our review methods will follow the reporting and conduct guidelines of the Cochrane Handbook for Systematic Reviews of Interventions and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis.
Ethical approval is not required as this project does not involve primary data collection. We will disseminate our findings through peer-reviewed publications and conference presentations.
CRD42020157851.
痴呆症是一个公共卫生问题，也是老年人生活质量低下的主要风险因素。在无法治愈的情况下，提高痴呆症患者的健康相关生活质量（HRQoL）是护理的首要目标。对HRQoL进行可靠测量是有效改善的先决条件。DEMQOL系列工具被认为是测量痴呆症患者HRQoL的最佳可用工具之一；然而，尚无综述系统全面地考察DEMQOL在研究中的应用，并总结证据以确定其在研究和实践中的可行性、可接受性和适用性。
我们将系统检索12个电子数据库以及所有纳入研究的参考文献列表。我们将纳入系统开展的综述，以及报告DEMQOL任何工具的开发、验证或在研究中的应用的定量和定性研究。两名评审员将独立筛选所有研究的纳入资格，并使用适用于不同研究设计的四份经过验证的清单之一评估每项纳入研究的质量。综述各阶段的分歧将通过协商解决。我们将使用描述性统计（频率、比例、范围）、叙事数据的内容分析和投票计数（用于关联度量）来汇总数据元素。通过叙事综合，我们将总结关于DEMQOL的开发、验证、可行性、可接受性、适用性和应用的已知信息。我们的综述方法将遵循《Cochrane干预措施系统评价手册》和《系统评价与Meta分析优先报告项目》的报告和实施指南。
由于本项目不涉及原始数据收集，因此无需伦理批准。我们将通过同行评审出版物和会议报告来传播我们的研究结果。
PROSPERO注册号：CRD42020157851。
