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[头颈部鳞状细胞癌复发与远处转移的治疗:2015年美国临床肿瘤学会会议要点]

[Treatment of head and neck squamous cell carcinoma recurrences and distant metastases: Highlights of the ASCO Meeting 2015].

作者信息

Bußmann L, Busch C-J, Knecht R

机构信息

Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Kopf-Hals-Chirurgie und Onkologie, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland.

出版信息

HNO. 2015 Sep;63(9):620-4. doi: 10.1007/s00106-015-0055-0.

Abstract

This year also saw a great number of phase II and III studies presented at the ASCO Annual Meeting, in which new drugs (monoclonal antibodies, small molecules) were investigated as an alternative to or in combination with established mono- and polychemotherapy in patients with recurrences or distance metastases from head and neck squamous cell carcinoma (R/M-HNSCC). The studies now presented here describe the different concepts being applied to drug-based treatment of R/M-HNSCC and illustrate the variety of therapeutic approaches to treatment of recurrences and metastases.

摘要

今年,也有大量的II期和III期研究在ASCO年会上发表,其中研究了新药(单克隆抗体、小分子药物)作为头颈部鳞状细胞癌复发或远处转移(R/M-HNSCC)患者既定单药和多药化疗的替代方案或联合用药方案。本文展示的研究描述了应用于R/M-HNSCC药物治疗的不同概念,并阐明了治疗复发和转移的多种治疗方法。

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