新诊断心肌梗死患者的高甘油三酯性腰围（EWET）、糖代谢及血脂谱

HYPERTRIGLYCERIDEMIC WAIST (EWET), GLYCIDIC AND LIPID PROFILE IN PATIENTS WITH NEWLY DIAGNOSED HEART ATTACK.

作者信息

Guattini Veronica Lucas de Olivera, Piovesan Carla Haas, Wittke Estefânia, Marcadenti Aline

机构信息

Postgraduate Studies Program in Cardiology, Instituto de Cardiologia/Fundação Universitária de Cardiologia do Rio Grande do Sul (IC/FUC), Porto Alegre, RS..

Department of Nutrition, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS..

出版信息

Nutr Hosp. 2015 Sep 1;32(3):1004-8. doi: 10.3305/nh.2015.32.3.9309.

DOI:10.3305/nh.2015.32.3.9309

PMID:26319812

Abstract

INTRODUCTION

hypertriglyceridemic waist phenotype (EWET) has been poorly tested in patients with established cardiovascular disease.

OBJECTIVES

to evaluate a possible association between EWET, glycidic and lipid profile in patients with newly diagnosed heart attack (HA).

METHODS

cross-sectional study among 45 inpatients with myocardial infarction. Lipid profile (total cholesterol, HDL-c, LDL-c, serum triglycerides, TC/HDL-c ratio, non-HDL cholesterol) and glycidic profile (fasting glucose, serum insulin, glycated hemoglobin, HOMA-IR, glucose/insulin ratio) were obtained. Weight, height and waist circumferences (WC) were assessed; BMI and EWET were calculated. Analysis of Covariance Models (ANCOVA) was used to assess the objectives.

RESULTS

mean age of participants was 58.75 ± 12.41 years and 55.6% (n = 25) were men. After adjustment for age, gender and BMI, EWET was significantly associated with lower HDL-c (p = 0.02), higher TC/HDL-c ratio (p = 0.003) and a trend toward fasting glucose (p = 0.11).

CONCLUSION

EWET phenotype seems to be associated with a worse lipidic profile in patients with newly diagnosed HA.

摘要

引言

高甘油三酯腰围表型（EWET）在已确诊心血管疾病的患者中研究较少。

目的

评估新诊断心肌梗死（HA）患者中EWET与糖脂谱之间的可能关联。

方法

对45例心肌梗死住院患者进行横断面研究。获取血脂谱（总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、血清甘油三酯、总胆固醇/高密度脂蛋白胆固醇比值、非高密度脂蛋白胆固醇）和糖谱（空腹血糖、血清胰岛素、糖化血红蛋白、胰岛素抵抗指数、血糖/胰岛素比值）。测量体重、身高和腰围（WC）；计算体重指数（BMI）和EWET。采用协方差分析模型（ANCOVA）评估研究目的。