Escaffi Fonseca María José, Moreira Carrasco Loreto, Rodríguez Osiac Lorena, Pizarro Quevedo Tito, Cavada Chacón Gabriel, Villarroel del Pino Luis, Salas Guzmán Natalia, Muzzo Benavides Santiago, Mönckeberg Barros Fernando, Rozowski Narkunska Jaime, Castillo Valenzuela Oscar
Programa de Magister en Nutrición, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago..
Corporación para la Nutrición Infantil, Santiago..
Nutr Hosp. 2015 Sep 1;32(3):1116-21. doi: 10.3305/nh.2015.32.3.9395.
during recent years consistent studies have characterized the relationship between moderate and severe protein-calorie malnutrition and the appearance of non-communicable diseases in adulthood like metabolic syndrome (MS).
to analyze the relationship between moderate and severe protein-calorie malnutrition during the first 1 000 days of life and the MS in a cohort of adults from Curicó, Chile.
we studied 49 young adults who had suffered moderate to severe protein-calorie malnutrition during their first two years of life. Anthropometry, blood pressure measurement and laboratory tests were performed, and the burden of MS attributes was determined.
the prevalence of MS was 14.3% with no significant differences by gender, showing a direct and significant association between burden of MS and body mass index, waist / height index, blood pressure, plasma levels of glucose and triglyceride, and an inverse association with HDL.
systolic blood pressure and plasma level of triglyceride represented the most important risk factors for SM in this cohort. We found no association between the presence of protein-calorie malnutrition and MS.
近年来，持续的研究已明确了中度和重度蛋白质 - 热量营养不良与成年期非传染性疾病（如代谢综合征，MS）出现之间的关系。
分析智利库里科一组成年人在生命最初1000天内中度和重度蛋白质 - 热量营养不良与代谢综合征之间的关系。
我们研究了49名在生命最初两年遭受中度至重度蛋白质 - 热量营养不良的年轻人。进行了人体测量、血压测量和实验室检查，并确定了代谢综合征各项指标的负担情况。
代谢综合征的患病率为14.3%，按性别无显著差异，显示代谢综合征负担与体重指数、腰/高指数、血压、血糖和甘油三酯血浆水平之间存在直接且显著的关联，与高密度脂蛋白呈负相关。
收缩压和甘油三酯血浆水平是该队列中代谢综合征最重要的危险因素。我们未发现蛋白质 - 热量营养不良的存在与代谢综合征之间存在关联。
