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红肉、微量营养素与阿根廷成年患者口腔鳞状细胞癌

RED MEAT, MICRONUTRIENTS AND ORAL SQUAMOUS CELL CARCINOMA OF ARGENTINE ADULT PATIENTS.

作者信息

Secchi Dante Gustavo, Aballay Laura Rosana, Galíndez María Fernanda, Piccini Daniel, Lanfranchi Héctor, Brunotto Mabel

机构信息

Departamento de Patología Bucal, Facultad de Odontología, Universidad Nacional de Córdoba..

Escuela de Nutrición, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba..

出版信息

Nutr Hosp. 2015 Sep 1;32(3):1214-21. doi: 10.3305/nh.2015.32.3.9277.

DOI:10.3305/nh.2015.32.3.9277
PMID:26319841
Abstract

INTRODUCTION

the identification of risk group of oral cancer allows reducing the typical morbidity and mortality rates of this pathology.

OBJETIVE

it was analyzed the role of red meat, macronutrients and micronutrients on Oral Squamous Cell carcinoma (OSCC) in a case-control study carried out in Cordoba, Argentina.

METHODS

case-control study 3:1, both genders, aged 24-80 years. Dietary information was collected using a quali-quantitative food frequency questionnaire. The logistic regression was applied for assessing the association among case/control status and daily red meat/macronutrient/ micronutrients/energy intake.

RESULTS

micronutrients and minerals in the diet that showed high significant median values of common consumption in cases relative to controls were iron, phosphorus, vitamins B1, B5, B6, E and K and selenium. The association measurement estimated by logistic regression was showed that a significant association between red meat, fat, daily energy, phosphorous, vitamin B5, vitamin E, and selenium intake and OSCC presence.

CONCLUSIONS

a high intake of fats, phosphorus, vitamin B5, vitamin E, and selenium intake and red meat appears to be related to the presence OSCC in Cordoba, Argentina. In relation to red meat consumption and risk of OSCC, the future research should center of attention on reducing the complexity of diet and disease relationships and reducing variability in intake data by standardizing of criteria in order to implement simple strategies in public health for recognizing risk groups of OSCC.

摘要

引言

确定口腔癌风险群体有助于降低该疾病的典型发病率和死亡率。

目的

在阿根廷科尔多瓦进行的一项病例对照研究中,分析红肉、常量营养素和微量营养素在口腔鳞状细胞癌(OSCC)中的作用。

方法

病例对照研究,比例为3:1,涵盖男女两性,年龄在24至80岁之间。使用定性定量食物频率问卷收集饮食信息。应用逻辑回归评估病例/对照状态与每日红肉/常量营养素/微量营养素/能量摄入之间的关联。

结果

与对照组相比,病例组中常见摄入量中位数具有高度显著差异的饮食中的微量营养素和矿物质有铁、磷、维生素B1、B5、B6、E和K以及硒。逻辑回归估计的关联测量结果表明,红肉、脂肪、每日能量、磷、维生素B5、维生素E和硒的摄入量与OSCC的存在之间存在显著关联。

结论

在阿根廷科尔多瓦,高脂肪、磷、维生素B5、维生素E和硒的摄入量以及红肉摄入量似乎与OSCC的存在有关。关于红肉消费与OSCC风险,未来的研究应集中于通过标准化标准来降低饮食与疾病关系的复杂性以及减少摄入数据的变异性,以便在公共卫生中实施简单策略来识别OSCC风险群体。

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