Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan.
Cancer Treat Res. 2024;191:145-161. doi: 10.1007/978-3-031-55622-7_6.
Cancer, a non-communicable disease with diverse kinds is one of the major global problems with high incidence and no proven method to prevent or treat. Minerals including trace elements are significant micronutrients for preserving the body's typical physiological function. In contrast to extremely processed industrial food, they are rich in natural sources of food and frequently included in nutritional supplements. The daily intake, storage capacities, and homeostasis of micronutrients depend on specific dietary practices in contemporary civilization and can be disturbed by various malignancies. Varied minerals have different effects on the status of cancer depending on how they affect these pathways. The outcomes could differ depending on the mineral such as calcium's supply and the cancer's location. A mineral called zinc helps the immune system function better and aids in wound healing. On the other hand, selenium exhibits anti-oxidant functions and has a dose-response relationship with many cancer types. However, this component can make the patient's condition worse. Although the body produces free radicals when iron is deficient, anaemia affects a patient's quality of life and ability to receive therapy. This chapter compiles the knowledge of minerals connected to unusual accumulation or depletion states in various malignancies.
癌症是一种非传染性疾病，具有多种类型，是全球主要问题之一，其发病率高，尚无预防或治疗方法。矿物质包括微量元素，是维持人体正常生理功能的重要微量营养素。与经过高度加工的工业食品不同，它们富含天然食物来源，并经常包含在营养补充剂中。在当代文明中，微量元素的每日摄入量、储存能力和体内平衡取决于特定的饮食实践，并且可能会受到各种恶性肿瘤的干扰。不同的矿物质对癌症状态有不同的影响，具体取决于它们对这些途径的影响。结果可能因矿物质的不同而有所不同，例如钙的供应和癌症的位置。一种叫做锌的矿物质有助于免疫系统更好地发挥功能，并有助于伤口愈合。另一方面，硒具有抗氧化功能，与许多癌症类型呈剂量反应关系。然而，这种成分可能会使患者的病情恶化。虽然缺铁时身体会产生自由基，但贫血会影响患者的生活质量和接受治疗的能力。本章汇集了与各种恶性肿瘤中异常积累或耗竭状态相关的矿物质知识。
