Haldar Sumanto, Chia Siok Ching, Henry Christiani Jeyakumar
Clinical Nutrition Research Centre (CNRC), Centre for Translational Medicine, Yong Loo Lin School of Medicine, Singapore; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore.
Clinical Nutrition Research Centre (CNRC), Centre for Translational Medicine, Yong Loo Lin School of Medicine, Singapore; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore.
Adv Food Nutr Res. 2015;75:97-154. doi: 10.1016/bs.afnr.2015.07.001. Epub 2015 Aug 12.
Within the last four decades Asia has witnessed major transformation in its population demographics, which gave rise to changes in food availability, food habits and lifestyle. A significant consequence of these changes has been the continuing rise in overweight and obesity across Asia. In parallel, there has been a significant rise in Asians in the incidence of the major chronic diseases, particularly in cardiometabolic disorders such as metabolic syndrome, type 2 diabetes, hypertension, and other cardiovascular diseases. Given that the majority of the evidence, to date, investigating the associations between adiposity and cardiometabolic disorder risk have been obtained from studies undertaken either in European or in North American Caucasians, in this chapter, we have reviewed differences in body fat content and distribution between East Asians, South Asians, and Caucasians. The evidence is consistent that the content and distribution of body fat are markedly different between the various ethnic groups. We found that Asians have a greater predisposition towards adiposity at higher BMI than in Caucasians. Moreover, at any given level of adiposity, Asians have a much greater predisposition to risk of cardiometabolic disorders than Caucasians. We therefore strongly endorse the need for different adiposity cutoffs in Asians as compared to the Caucasians. We have also reviewed the predictive abilities of the various body composition/adiposity measures in determining risk of cardiometabolic disorders in Asians.
在过去的四十年里,亚洲的人口结构发生了重大转变,这导致了食物供应、饮食习惯和生活方式的变化。这些变化的一个重要后果是亚洲超重和肥胖人数持续上升。与此同时,亚洲主要慢性病的发病率显著上升,尤其是在代谢综合征、2型糖尿病、高血压和其他心血管疾病等心脏代谢紊乱方面。鉴于迄今为止,大多数关于肥胖与心脏代谢紊乱风险之间关联的证据都来自对欧洲或北美白种人进行的研究,在本章中,我们回顾了东亚人、南亚人和白种人在体脂含量和分布上的差异。有证据一致表明,不同种族群体之间的体脂含量和分布明显不同。我们发现,亚洲人在较高体重指数(BMI)时比白种人更容易肥胖。此外,在任何给定的肥胖水平下,亚洲人比白种人更容易患心脏代谢紊乱疾病。因此,我们强烈支持亚洲人与白种人相比需要不同的肥胖临界值。我们还回顾了各种身体成分/肥胖测量方法在确定亚洲人心脏代谢紊乱风险方面的预测能力。