Sobra J, Páv J, Ceska R
Cas Lek Cesk. 1989 Dec 8;128(50):1575-9.
Cardiovascular diseases are the most frequent cause of mortality in the sub-population of type II diabetics (cca 600,000 in the CSSR). Type II diabetics very frequently cumulate several very serious risk factors (hyperlipoproteinaemia, arterial hypertension, obesity, hyperuricaemia, smoking) for the manifestation of cardiovascular disease. Concurrent comprehensive treatment of all revealed risk factors is essential for primary prevention. Systematic application of methods of genetic epidemiology in families of affected diabetics helps to detect in time and to treat other affected members of the family. It is at the same time a rational way of primary prevention of cardiovascular disease in the highest risk sub-populations. The authors submit an algorithm of treatment of hyperlipoproteinaemic type II diabetics.
心血管疾病是II型糖尿病亚人群中最常见的死亡原因（在捷克斯洛伐克社会主义共和国约有60万例）。II型糖尿病患者常常同时存在几种非常严重的心血管疾病危险因素（高脂蛋白血症、动脉高血压、肥胖、高尿酸血症、吸烟）。对所有已发现的危险因素进行综合治疗对于一级预防至关重要。在受影响的糖尿病患者家庭中系统应用遗传流行病学方法有助于及时发现并治疗家庭中的其他患病成员。这同时也是在高危亚人群中进行心血管疾病一级预防的合理方法。作者提出了高脂蛋白血症II型糖尿病患者的治疗算法。
