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本文引用的文献

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Intraindividual variability is a fundamental phenomenon of aging: evidence from an 8-year longitudinal study across young, middle, and older adulthood.个体内变异性是衰老的一个基本现象:来自跨越青年、中年和老年期的 8 年纵向研究的证据。
Dev Psychol. 2014 Jan;50(1):143-51. doi: 10.1037/a0032650. Epub 2013 Apr 15.
2
Race-ethnicity and health trajectories: tests of three hypotheses across multiple groups and health outcomes.种族-民族与健康轨迹:跨多个群体和健康结果检验三种假说。
J Health Soc Behav. 2012 Sep;53(3):359-77. doi: 10.1177/0022146512455333.
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Racial differences in depression trajectories among older women: socioeconomic, family, and health influences.老年人抑郁症轨迹的种族差异:社会经济、家庭和健康的影响。
J Health Soc Behav. 2011 Dec;52(4):444-59. doi: 10.1177/0022146511410432. Epub 2011 Oct 21.
4
Assessment of cognition using surveys and neuropsychological assessment: the Health and Retirement Study and the Aging, Demographics, and Memory Study.使用问卷调查和神经心理学评估进行认知评估:健康与退休研究以及老龄化、人口统计学和记忆研究。
J Gerontol B Psychol Sci Soc Sci. 2011 Jul;66 Suppl 1(Suppl 1):i162-71. doi: 10.1093/geronb/gbr048.
5
Developmental change and intraindividual variability: relating cognitive aging to cognitive plasticity, cardiovascular lability, and emotional diversity.发展变化与个体内变异性:将认知老化与认知可塑性、心血管变异性和情绪多样性联系起来。
Psychol Aging. 2011 Jun;26(2):363-71. doi: 10.1037/a0021500.
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Modeling transition rates using panel current-status data: how serious is the bias?使用面板当前状态数据对转移率进行建模:偏差有多严重?
Demography. 2009 May;46(2):371-86. doi: 10.1353/dem.0.0057.
7
Ageing and gait variability--a population-based study of older people.年龄与步态变异性——一项基于人群的老年人研究。
Age Ageing. 2010 Mar;39(2):191-7. doi: 10.1093/ageing/afp250. Epub 2010 Jan 18.
8
Aging, time scales, and sensorimotor variability.衰老、时间尺度和感觉运动变异性。
Psychol Aging. 2009 Dec;24(4):809-18. doi: 10.1037/a0017911.
9
Education and Cognitive Decline in Older Americans: Results From the AHEAD Sample.美国老年人的教育与认知衰退:来自“老年人健康与经济状况前瞻性研究”(AHEAD)样本的结果
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Latent variable analyses of age trends of cognition in the Health and Retirement Study, 1992-2004.1992 - 2004年健康与退休研究中认知年龄趋势的潜在变量分析
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从噪音到信号:晚年健康个体内部变异性的年龄和社会模式

From Noise to Signal: The Age and Social Patterning of Intra-Individual Variability in Late-Life Health.

作者信息

Lin Jielu, Kelley-Moore Jessica A

机构信息

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.

Department of Sociology, Case Western Reserve University, Cleveland, Ohio.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2017 Jan;72(1):168-179. doi: 10.1093/geronb/gbv081. Epub 2015 Aug 29.

DOI:10.1093/geronb/gbv081
PMID:26320123
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5156487/
Abstract

OBJECTIVES

Despite a long tradition of attending to issues of intra-individual variability in the gerontological literature, large-scale panel studies on late-life health disparities have primarily relied on average health trajectories, relegating intra-individual variability over time to random error terms, or "noise." This article reintegrates the systematic study of intra-individual variability back into standard growth curve modeling and investigates the age and social patterning of intra-individual variability in health trajectories.

METHOD

Using panel data from the Health and Retirement Study, we estimate multilevel growth curves of functional limitations and cognitive impairment and examine whether intra-individual variability in these two health outcomes varies by age, gender, race/ethnicity, and socioeconomic status, using level-1 residuals extracted from the adjusted growth curve models.

RESULTS

For both outcomes, intra-individual variability increases with age. Racial/ethnic minorities and individuals with lower socioeconomic status tend to have greater intra-individual variability in health. Relying exclusively on average health trajectories may have masked important "signals" of life course health inequality.

DISCUSSION

The findings contribute to scientific understanding of the source of heterogeneity in late-life health and highlight the need to further investigate specific life course mechanisms that generate the social patterning of intra-individual variability in health status.

摘要

目标

尽管老年学文献长期以来一直关注个体内部变异性问题,但关于晚年健康差异的大规模面板研究主要依赖于平均健康轨迹,将个体随时间的变异性归结为随机误差项或“噪声”。本文将个体内部变异性的系统研究重新纳入标准增长曲线模型,并研究健康轨迹中个体内部变异性的年龄和社会模式。

方法

利用健康与退休研究的面板数据,我们估计了功能受限和认知障碍的多层次增长曲线,并使用从调整后的增长曲线模型中提取的一级残差,检验这两种健康结果的个体内部变异性是否因年龄、性别、种族/民族和社会经济地位而异。

结果

对于这两种结果,个体内部变异性均随年龄增长而增加。少数族裔和社会经济地位较低的个体在健康方面往往具有更大的个体内部变异性。仅依赖平均健康轨迹可能掩盖了生命历程健康不平等的重要“信号”。

讨论

这些发现有助于科学理解晚年健康异质性的来源,并强调需要进一步研究产生健康状况个体内部变异性社会模式的具体生命历程机制。