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前交叉韧带重建与软骨接触力——三维计算模拟

Anterior cruciate ligament reconstruction and cartilage contact forces--A 3D computational simulation.

作者信息

Wang Lianxin, Lin Lin, Feng Yong, Fernandes Tiago Lazzaretti, Asnis Peter, Hosseini Ali, Li Guoan

机构信息

Bioengineering Laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA; Department of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, PR China.

Bioengineering Laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA; Institute of Sports Medicine, Peking University Third Hospital, North Garden Road, Haidian District, Beijing 100191, PR China.

出版信息

Clin Biomech (Bristol). 2015 Dec;30(10):1175-80. doi: 10.1016/j.clinbiomech.2015.08.007. Epub 2015 Aug 18.

Abstract

BACKGROUND

Clinical outcome studies showed a high incidence of knee osteoarthritis after anterior cruciate ligament reconstruction. Abnormal joint kinematics and loading conditions were assumed as risking factors. However, little is known on cartilage contact forces after the surgery.

METHODS

A validated computational model was used to simulate anatomic and transtibial single-bundle anterior cruciate ligament reconstructions. Two graft fixation angles (0° and 30°) were simulated for each reconstruction. Biomechanics of the knee was investigated in intact, anterior cruciate ligament deficient and reconstructed conditions when the knee was subjected to 134 N anterior load and 400 N quadriceps load at 0°, 30°, 60° and 90° of flexion. The tibial translation and rotation, graft forces, medial and lateral contact forces were calculated.

FINDINGS

When the graft was fixed at 0°, the anatomic reconstruction resulted in slightly larger lateral contact force at 0° compared to the intact knee while the transtibial technique led to higher contact force at both 0° and 30° under the muscle load. When graft was fixed at 30°, the anatomic reconstruction overstrained the knee at 0° with larger contact forces, while the transtibial technique resulted in slightly larger contact forces at 30°.

INTERPRETATION

This study suggests that neither the anatomic nor the transtibial reconstruction can consistently restore normal knee biomechanics at different flexion angles. The anatomic reconstruction may better restore anteroposterior stability and contact force with the graft fixed at 0°. The transtibial technique may better restore knee anteroposterior stability and articular contact force with the graft fixed at 30° of flexion.

摘要

背景

临床结局研究表明,前交叉韧带重建术后膝关节骨关节炎的发生率很高。异常的关节运动学和负荷情况被认为是危险因素。然而,关于手术后软骨接触力的了解甚少。

方法

使用经过验证的计算模型来模拟解剖学和经胫骨单束前交叉韧带重建。每种重建模拟两种移植物固定角度(0°和30°)。当膝关节在0°、30°、60°和90°屈曲时承受134 N前向负荷和400 N股四头肌负荷时,研究完整、前交叉韧带缺失和重建状态下膝关节的生物力学。计算胫骨平移和旋转、移植物力、内侧和外侧接触力。

结果

当移植物固定在0°时,解剖重建在0°时导致的外侧接触力比完整膝关节略大,而经胫骨技术在肌肉负荷下在0°和30°时导致更高的接触力。当移植物固定在30°时,解剖重建在0°时使膝关节过度受力,接触力更大,而经胫骨技术在30°时导致略大的接触力。

解读

本研究表明,解剖重建和经胫骨重建均不能在不同屈曲角度始终如一地恢复正常膝关节生物力学。当移植物固定在0°时,解剖重建可能更好地恢复前后稳定性和接触力。当移植物固定在屈曲30°时,经胫骨技术可能更好地恢复膝关节前后稳定性和关节接触力。

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