Böttcher Sindy, Neubauer Katrin, Baillot Armin, Rieder Gabriele, Adam Maja, Diedrich Sabine
National Reference Laboratory for Poliomyelitis and Enteroviruses, Robert Koch Institute, PO Box 65 02 61, 13302 Berlin, Germany.
Office of the National Commission for Polioeradication in Germany, Robert Koch Institute, Berlin, Germany.
Int J Med Microbiol. 2015 Oct;305(7):601-6. doi: 10.1016/j.ijmm.2015.08.008. Epub 2015 Aug 21.
Germany is a partner of the Global Polio Eradication Initiative. Assurance of polio free status is based on enterovirus surveillance, which focuses on patients with signs of acute flaccid paralysis or aseptic meningitis/encephalitis, representing the key symptoms of poliovirus infection. In response to the wild poliovirus outbreak in Syria 2013 and high number of refugees coming from Syria to Germany, stool samples from 629 Syrian refugees/asylum seekers aged <3 years were screened for wild poliovirus between November 2013 and April 2014. Ninety-three samples (14.8%) were positive in an enterovirus specific PCR. Of these, 12 contained Sabin-like polioviruses. The remaining 81 samples were characterized as non-polio enteroviruses representing several members of groups A-C as well as rhinovirus. Wild-type poliovirus was not detected via stool screening involving molecular and virological methods, indicating a very low risk for the importation by Syrian refugees and asylum seekers at that time.
德国是全球根除脊髓灰质炎行动的合作伙伴。无脊髓灰质炎状态的确认基于肠道病毒监测，该监测聚焦于患有急性弛缓性麻痹体征或无菌性脑膜炎/脑炎的患者，这些是脊髓灰质炎病毒感染的关键症状。为应对2013年叙利亚野生脊髓灰质炎病毒疫情以及大量叙利亚难民涌入德国的情况，在2013年11月至2014年4月期间，对629名年龄小于3岁的叙利亚难民/寻求庇护者的粪便样本进行了野生脊髓灰质炎病毒筛查。在肠道病毒特异性聚合酶链反应中，93份样本（14.8%）呈阳性。其中，12份含有萨宾样脊髓灰质炎病毒。其余81份样本被鉴定为非脊髓灰质炎肠道病毒，代表A - C组的几个成员以及鼻病毒。通过涉及分子和病毒学方法的粪便筛查未检测到野生型脊髓灰质炎病毒，这表明当时叙利亚难民和寻求庇护者输入脊髓灰质炎病毒的风险非常低。
