Kerridge Bradley T, Saha Tulshi D, Hasin Deborah S
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168 Street, New York, NY, 10032.
Laboratory of Epidemiology and Biometry, Intramural Division of Clinical and Biological Research, National Institutes on Alcohol Abuse and Alcoholism, National Institutes of Health, 5636 Fishers Lane, Rockville, Maryland, 20852.
Ment Health Subst Use. 2014;7(4):446-460. doi: 10.1080/17523281.2014.946076.
This study examined the underlying structure of DSM-IV schizotypal personality disorder (SPD) among individuals with and without a substance use disorder. Using a nationally representative sample of U.S. adults, taxometric analyses were conducted on SPD in the total sample and among individuals with and without a substance use disorder. The structure of SPD in the total sample and among individuals without substance use disorders was dimensional (comparison curve fit indices (CCFI): 0.440, 0.365) whereas a taxonic structure was demonstrated among individuals with a substance use disorder (CCFI: 0.679). Taxonicity underlying schizotypy and SPD in prior taxometric research may have been the result of sampling high risk subsamples of the population. Taxometric research on SPD and other personality psychopathology among high risk subgroups of the population can help elucidate the complex etiology of SPD and the role played by comorbid substance use disorders in the expressivity of these disorders.
本研究调查了患有和未患有物质使用障碍的个体中《精神疾病诊断与统计手册》第四版（DSM-IV）精神分裂样人格障碍（SPD）的潜在结构。利用美国成年人的全国代表性样本，对总样本以及患有和未患有物质使用障碍的个体进行了关于SPD的分类分析。总样本以及未患有物质使用障碍的个体中SPD的结构呈维度性（比较曲线拟合指数（CCFI）：0.440，0.365），而在患有物质使用障碍的个体中呈现出类属结构（CCFI：0.679）。先前分类分析研究中精神分裂症样症状和SPD的类属性可能是对该人群高风险子样本进行抽样的结果。对该人群高风险亚组中的SPD和其他人格精神病理学进行分类分析研究，有助于阐明SPD的复杂病因以及共病物质使用障碍在这些障碍表现中的作用。
