Di Simplicio Martina, Holmes Emily A, Rathbone Clare J
MRC Cognition and Brain Sciences Unit, Cambridge,UK.
MRC Cognition and Brain Sciences Unit, Cambridge,UK; Department of Clinical Neuroscience, Karonlinska Institutet, Stockholm, Sweden.
J Affect Disord. 2015 Nov 15;187:97-100. doi: 10.1016/j.jad.2015.08.042. Epub 2015 Aug 21.
Bipolar Spectrum Disorder (BPSD) is associated with changes in self-related processing and affect, yet the relationship between self-image and affect in the BPSD phenotype is unclear.
47 young adults were assessed for hypomanic experiences (BPSD phenotype) using the Mood Disorders Questionnaire. Current and future self-images (e.g. I am… I will be…) were generated and rated for emotional valence, stability, and (for future self-images only) certainty. The relationship between self-image ratings and measures of affect (depression, anxiety and mania) were analysed in relation to the BPSD phenotype.
The presence of the BPSD phenotype significantly moderated the relationship between (1) affect and stability ratings for negative self-images, and (2) affect and certainty ratings for positive future self-images. Higher positivity ratings for current self-images were associated with lower depression and anxiety scores.
This was a non-clinical group of young adults sampled for hypomanic experiences, which limits the extension of the work to clinical levels of psychopathology. This study cannot address the causal relationships between affect, self-images, and BPSD. Future work should use clinical samples and experimental mood manipulation designs.
BPSD phenotype can shape the relationship between affect and current and future self-images. This finding will guide future clinical research to elucidate BPSD vulnerability mechanisms and, consequently, the development of early interventions.
双相谱系障碍(BPSD)与自我相关加工及情感的变化有关,但BPSD表型中自我形象与情感之间的关系尚不清楚。
使用心境障碍问卷对47名年轻成年人进行轻躁狂体验(BPSD表型)评估。生成当前和未来的自我形象(例如“我是……我将成为……”),并对其情感效价、稳定性以及(仅针对未来自我形象)确定性进行评分。分析自我形象评分与情感测量指标(抑郁、焦虑和躁狂)之间的关系,并与BPSD表型相关联。
BPSD表型的存在显著调节了以下两种关系:(1)负面自我形象的情感与稳定性评分之间的关系,以及(2)正面未来自我形象的情感与确定性评分之间的关系。当前自我形象的较高积极评分与较低的抑郁和焦虑得分相关。
这是一组因轻躁狂体验而抽样的非临床年轻成年人,这限制了该研究成果向临床精神病理学水平的扩展。本研究无法解决情感、自我形象和BPSD之间的因果关系。未来的研究应使用临床样本和实验性情绪操纵设计。
BPSD表型可塑造情感与当前及未来自我形象之间的关系。这一发现将指导未来的临床研究,以阐明BPSD的易感性机制,从而推动早期干预措施的发展。