a Department of Environmental Chemistry and Bioanalytics , Nicolaus Copernicus University , Toruń , Poland.
b Interdisciplinary Centre for Modern Technologies, Nicolaus Copernicus University , Toruń , Poland.
Crit Rev Anal Chem. 2016 May 3;46(3):236-47. doi: 10.1080/10408347.2015.1081051.
Biologically active compounds constitute a wide group of chemicals, therefore it is a big challenge to create sorbents that are sensitive as well as selective. Development of nanoporous sorbents based on conducting polymers has expanded the boundaries of detection and quantification. Additionally, electrochemical synthesis used to deposit polymeric coatings directly on solid supports makes it possible to control physico-chemical properties of such sorbents. Besides the development of new polymeric nanoporous materials, the question of selectivity needs to be addressed. One possibility, successfully adapted to solid-phase microextraction, is molecular imprinting. Coatings created with this technology allow obtaining higher selectivity, with sensitivity at a constantly high level. The main aim of this review is to present comprehensively the concept of nanoporous sorbents based on conducting polymers, possible coating methods with their characteristics, and their various applications. This article focuses on applications in environmental and biomedical analyses.
生物活性化合物构成了广泛的化学物质群体，因此，创造既敏感又有选择性的吸附剂是一项巨大的挑战。基于导电聚合物的纳米多孔吸附剂的发展扩大了检测和定量的范围。此外，用于直接在固体载体上沉积聚合物涂层的电化学合成使得控制此类吸附剂的物理化学性质成为可能。除了开发新型聚合物纳米多孔材料外，还需要解决选择性问题。一种成功应用于固相微萃取的方法是分子印迹。使用该技术制备的涂层可获得更高的选择性，同时保持高灵敏度。本综述的主要目的是全面介绍基于导电聚合物的纳米多孔吸附剂的概念、可能的涂层方法及其各种应用。本文重点介绍在环境和生物医学分析中的应用。
