Yuan Rong, Wang Jie, Guo Li-li
Zhongguo Zhong Yao Za Zhi. 2015 May;40(9):1666-9.
Sleep deprivation (SD) has been taken as an independent predictor for cardiovascular risks, which was closely related to the increased morbidity and mortality in coronary heart disease (CHD). In this article, after reviewing the impact of modern medical method sleep deprivation on CHD and studies on principle method recipe medicines for preventing and treating CHD, the authors observed the autonomic nerve dysfunction, hormonal metabolism dysfunction, endothelial dysfunction and inflammatory responses after sleep deprivation, which can cause or aggravate CHD. On the basis of the traditional Chinese medicine theories of "heart dominating the blood and vessels and the mind", the authors considered that traditional Chinese medicines can tonify heart and soothe the nerves, reducing all of the risk factors through multi-target and multi-pathway, and improve sleep and decrease the risk factors caused by sleep deprivation, which provides a new idea for the prevention and treatment of CHD.
睡眠剥夺（SD）已被视为心血管风险的独立预测因素，这与冠心病（CHD）发病率和死亡率的增加密切相关。在本文中，作者在回顾现代医学方法睡眠剥夺对冠心病的影响以及防治冠心病的原则方法方剂药物研究后，观察到睡眠剥夺后自主神经功能障碍、激素代谢功能障碍、内皮功能障碍和炎症反应，这些可导致或加重冠心病。基于中医“心主血脉与神明”的理论，作者认为中药可养心安神，通过多靶点、多途径降低所有危险因素，改善睡眠并减少睡眠剥夺引起的危险因素，为冠心病的防治提供了新思路。
