Yuan Rong, Wang Jie, Guo Lili
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053; Beijing University of Chinese Medicine, Beijing 100029.
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053.
Chin Med Sci J. 2016 Nov 20;31(4):247-253. doi: 10.1016/s1001-9294(17)30008-1.
Sleep deprivation (SD) has been associated with an increased morbidity and mortality of coronary heart disease (CHD). SD could induce autonomic nervous dysfunction, hypertension, arrhythmia, hormonal dysregulation, oxidative stress, endothelial dysfunction, inflammation and metabolic disorder in CHD patients. This paper reviewed the study results of SD in clinical trials and animal experiments and concluded that SD was associated with cardiovascular risk factors, which aggravated CHD in pathogenesis and outcomes.
睡眠剥夺（SD）与冠心病（CHD）的发病率和死亡率增加有关。睡眠剥夺可导致冠心病患者出现自主神经功能障碍、高血压、心律失常、激素失调、氧化应激、内皮功能障碍、炎症和代谢紊乱。本文综述了睡眠剥夺在临床试验和动物实验中的研究结果，得出结论：睡眠剥夺与心血管危险因素相关，在发病机制和预后方面加重了冠心病。
