Wang Tao, Shen Xue-gen, Guo Qiao-sheng, Zhou Jian-song, Mao Peng-fei, Shen Zhen-guo
Zhongguo Zhong Yao Za Zhi. 2015 May;40(9):1670-5.
Leaves of Chrysanthemum morifolium were potential medicinal resource. The present study aims to estimate the main bioactive components: total flavonoids (TF), galuteolin (GA), quercitrin (QU), chlorogenic acid (CA) and 3 ,5-O-caffeoylquinic acid ( CQ), which were considered to be the main effective components, in leaves of C. morfolium cultivars in China. The TF content was estimated hy UV-VIS spectrophotometry, while GA, QU, CA, and CQ were quantitatively determined by HPLC. The highest TF content (7. 13% w/w) was found in cultivar Wan Cong (Shexian county). Cultivar Da Bo ( Bozhou county) had the highest GA content (33. 45 mg - g-1); Cultivar Hong Xin (Sheyang county) contained the highest QU content (29.25 mg · g(-1)); Cultivar Chang Ban (Sheyang county) had the highest CA content (13.14 mg ·(-1)). The maximum CQ content (7.35 mg · g(-1)) was observed in culti- r Da Yang ( Tongxiang county). Different cultivars of C. morfolium had significant difference in components, but the leaf and capitulum of C. morifolium. were found to possess similar chemical compositions. The high content of bioactive components in several cultivars suggested the potential utilization of C. morifolium leaves.
杭菊花的叶子是潜在的药用资源。本研究旨在评估中国杭菊品种叶片中的主要生物活性成分：总黄酮（TF）、木犀草素（GA）、槲皮苷（QU）、绿原酸（CA）和3,5 - O - 咖啡酰奎宁酸（CQ），这些被认为是主要的有效成分。TF含量通过紫外 - 可见分光光度法估算，而GA、QU、CA和CQ则通过高效液相色谱法定量测定。在品种皖菊（歙县）中发现TF含量最高（7.13% w/w）。品种大白（亳州）的GA含量最高（33.45 mg·g⁻¹）；品种红心（射阳）的QU含量最高（29.25 mg·g⁻¹）；品种长瓣（射阳）的CA含量最高（13.14 mg·g⁻¹）。在品种大洋（桐乡）中观察到CQ含量最高（7.35 mg·g⁻¹）。杭菊的不同品种在成分上有显著差异，但杭菊的叶片和头状花序具有相似的化学成分。几个品种中生物活性成分的高含量表明杭菊叶片具有潜在的利用价值。
