Woods Stephen C, Begg Denovan P
Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, 2170 East Galbraith Road, Cincinnati, OH, 45237, USA.
School of Psychology, University of New South Wales, Sydney, Australia.
Curr Top Behav Neurosci. 2016;27:15-34. doi: 10.1007/7854_2015_381.
Although food intake is necessary to provide energy for all bodily activities, considering food intake as a motivated behavior is complex. Rather than being a simple unconditioned reflex to energy need, eating is mediated by diverse factors. These include homeostatic signals such as those related to body fat stores, to food available and being eaten, and to circulating energy-rich compounds like glucose and fatty acids. Eating is also greatly influenced by non-homeostatic signals that convey information related to learning and experience, hedonics, stress, the social situation, opportunity, and many other factors. Recent developments identifying the intricate nature of the relationships between homeostatic and non-homeostatic influences significantly add to the complexity underlying the neural basis of the motivation to eat. The future of research in the field of food intake would seem to lie in the identification of the neural circuitry and interactions between homeostatic and non-homeostatic influences.
尽管摄入食物对于为身体所有活动提供能量是必要的,但将食物摄入视为一种有动机的行为是复杂的。进食并非是对能量需求的简单无条件反射,而是由多种因素介导的。这些因素包括稳态信号,如与身体脂肪储存、可获取和正在食用的食物以及循环中的富含能量的化合物(如葡萄糖和脂肪酸)相关的信号。进食还受到非稳态信号的极大影响,这些信号传达与学习和经验、享乐主义、压力、社会情境、机会以及许多其他因素相关的信息。最近对稳态和非稳态影响之间复杂关系的研究进展,显著增加了进食动机神经基础背后的复杂性。食物摄入领域的未来研究似乎在于确定稳态和非稳态影响之间的神经回路及相互作用。