Chen Xiaoping, Huang Yongshun, Yang Gang, Li Jiaxing, Wang Tingting, Schulz Olaf H, Jennings Lisa K
20 South Dudley, Suite 900, Memphis, TN 38103.
Curr Pharm Des. 2015;21(29):4262-75. doi: 10.2174/1381612821666150901103418.
In the past few decades, the applications of nanomaterials in biologic systems have become one of the most studied areas. Many novel syntheses and processing methods have been developed to generate nanomaterials to enhance biomedical applications. Among those methods, polydopamine (PDA) integrated nanomaterials have attracted considerable interest for various types of biomedical applications. This concise review outlines the basic chemistry and material science regarding PDA and discusses its successful applications in drug delivery, biosensing, antifouling and antimicrobial activities, as well as its interaction with cells.
在过去几十年中，纳米材料在生物系统中的应用已成为研究最多的领域之一。人们已开发出许多新颖的合成和加工方法来制备纳米材料，以增强其生物医学应用。在这些方法中，聚多巴胺（PDA）集成纳米材料在各类生物医学应用中引起了相当大的关注。本简要综述概述了关于PDA的基础化学和材料科学，并讨论了其在药物递送、生物传感、抗污和抗菌活性方面的成功应用，以及它与细胞的相互作用。
