Suppr超能文献

哺乳动物微生物组当前研究现状的最新进展

An Update on the Status of Current Research on the Mammalian Microbiome.

作者信息

Nelson Karen E

机构信息

Karen E. Nelson is President at the J. Craig Venter Institute (JCVI) in Rockville, Maryland.

出版信息

ILAR J. 2015;56(2):163-8. doi: 10.1093/ilar/ilv033.

Abstract

The microbiome refers to the thousands of microbial species that inhabit a specific host or environment. Extensive microbiome surveys have been conducted for soils, the built environment, and our oceans. In addition, extensive studies of the human microbiome have revealed significant microbial diversity across all body sites and have hinted at new opportunities for diagnostic and therapeutic approaches to addressing human health and disease. Mammals in general are known to hold a complicated mix of species within their gastrointestinal tracts, including virus, archaea, bacteria, and fungi. These microbial species present beneficial aspects to the host species through the production of vitamins, metabolism of plant structural compounds and sugars, and education of the immune system. In addition to a vast number of studies on humans, studies of the mammalian microbiome have been performed, with several publications on a variety of animal species currently available. These have included studies on the microbiome of companion animals, animals used for research, and animals used for agricultural and food purposes, and various human/animal models.

摘要

微生物组是指栖息在特定宿主或环境中的数千种微生物物种。已经对土壤、建筑环境和海洋进行了广泛的微生物组调查。此外,对人类微生物组的广泛研究揭示了所有身体部位都存在显著的微生物多样性,并暗示了在诊断和治疗方法方面存在解决人类健康和疾病问题的新机会。一般来说,哺乳动物的胃肠道内含有复杂的物种组合,包括病毒、古菌、细菌和真菌。这些微生物物种通过产生维生素、代谢植物结构化合物和糖类以及训练免疫系统,为宿主物种带来益处。除了对人类进行的大量研究外,也开展了对哺乳动物微生物组的研究,目前已有多篇关于各种动物物种的出版物。这些研究包括对伴侣动物、用于研究的动物、用于农业和食品目的的动物以及各种人类/动物模型的微生物组研究。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验