Stolarczyk Artur, Horvath Andrea, Szczechura Monika, Kamińska Magda, Dziechciarz Piotr
Clinical Rehabilitation Department, Medical University of Warsaw, Poland.
Department of Paediatrics, Medical University of Warsaw, Poland.
Prz Menopauzalny. 2014 Oct;13(5):289-92. doi: 10.5114/pm.2014.46471. Epub 2014 Nov 2.
Inadequate vitamin D level is associated with altered bone turnover and bone loss, which increases the fracture risk.
To assess the seasonal prevalence of inadequate (insufficient or deficient) serum vitamin D levels in community-dwelling postmenopausal Polish women screened for osteoporosis.
A cross-sectional observational study based on the regional urban non-institutionalized sample (n = 107) of postmenopausal Caucasian women in the age range of 51-83 years, not taking any medication and free from any condition likely to affect vitamin D status or calcium/bone metabolism. The outcome measures were the mean 25-OH vitamin D level across all the seasons and the percentage of vitamin D deficiency and insufficiency and defined as < 20 ng/dl (50 nmol/l) and 20-30 ng/dl (50-75 nmol/l), respectively.
No statistically significant difference has been found in the mean vitamin D level, regardless of the season (p = 0.4). The prevalence of vitamin D deficiency and insufficiency were in spring 54% and 32%, in summer 46% and 46%, in autumn 67% and 27%, and in winter 61% and 22%, respectively.
Vitamin D inadequacy is common in a sample of Polish community-dwelling postmenopausal women regardless of the season.
维生素D水平不足与骨转换改变和骨质流失有关，这会增加骨折风险。
评估在接受骨质疏松筛查的波兰社区绝经后女性中，血清维生素D水平不足（缺乏或不足）的季节性患病率。
一项横断面观察性研究，基于51 - 83岁绝经后白种女性的区域城市非机构化样本（n = 107），这些女性未服用任何药物，且没有任何可能影响维生素D状态或钙/骨代谢的疾病。观察指标为所有季节的平均25 - OH维生素D水平，以及维生素D缺乏和不足的百分比，分别定义为< 20 ng/dl（50 nmol/l）和20 - 30 ng/dl（50 - 75 nmol/l）。
无论季节如何，平均维生素D水平均未发现有统计学显著差异（p = 0.4）。维生素D缺乏和不足的患病率在春季分别为54%和32%，夏季分别为46%和46%，秋季分别为67%和27%，冬季分别为61%和22%。
在波兰社区居住的绝经后女性样本中，无论季节如何，维生素D不足都很常见。
