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波兰社区绝经后女性维生素D缺乏症的高患病率。

High prevalence of vitamin D insufficiency in community-dwelling postmenopausal Polish women.

作者信息

Stolarczyk Artur, Horvath Andrea, Szczechura Monika, Kamińska Magda, Dziechciarz Piotr

机构信息

Clinical Rehabilitation Department, Medical University of Warsaw, Poland.

Department of Paediatrics, Medical University of Warsaw, Poland.

出版信息

Prz Menopauzalny. 2014 Oct;13(5):289-92. doi: 10.5114/pm.2014.46471. Epub 2014 Nov 2.

Abstract

INTRODUCTION

Inadequate vitamin D level is associated with altered bone turnover and bone loss, which increases the fracture risk.

AIM

To assess the seasonal prevalence of inadequate (insufficient or deficient) serum vitamin D levels in community-dwelling postmenopausal Polish women screened for osteoporosis.

MATERIAL AND METHODS

A cross-sectional observational study based on the regional urban non-institutionalized sample (n = 107) of postmenopausal Caucasian women in the age range of 51-83 years, not taking any medication and free from any condition likely to affect vitamin D status or calcium/bone metabolism. The outcome measures were the mean 25-OH vitamin D level across all the seasons and the percentage of vitamin D deficiency and insufficiency and defined as < 20 ng/dl (50 nmol/l) and 20-30 ng/dl (50-75 nmol/l), respectively.

RESULTS

No statistically significant difference has been found in the mean vitamin D level, regardless of the season (p = 0.4). The prevalence of vitamin D deficiency and insufficiency were in spring 54% and 32%, in summer 46% and 46%, in autumn 67% and 27%, and in winter 61% and 22%, respectively.

CONCLUSIONS

Vitamin D inadequacy is common in a sample of Polish community-dwelling postmenopausal women regardless of the season.

摘要

引言

维生素D水平不足与骨转换改变和骨质流失有关,这会增加骨折风险。

目的

评估在接受骨质疏松筛查的波兰社区绝经后女性中,血清维生素D水平不足(缺乏或不足)的季节性患病率。

材料与方法

一项横断面观察性研究,基于51 - 83岁绝经后白种女性的区域城市非机构化样本(n = 107),这些女性未服用任何药物,且没有任何可能影响维生素D状态或钙/骨代谢的疾病。观察指标为所有季节的平均25 - OH维生素D水平,以及维生素D缺乏和不足的百分比,分别定义为< 20 ng/dl(50 nmol/l)和20 - 30 ng/dl(50 - 75 nmol/l)。

结果

无论季节如何,平均维生素D水平均未发现有统计学显著差异(p = 0.4)。维生素D缺乏和不足的患病率在春季分别为54%和32%,夏季分别为46%和46%,秋季分别为67%和27%,冬季分别为61%和22%。

结论

在波兰社区居住的绝经后女性样本中,无论季节如何,维生素D不足都很常见。

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