Koca Orhan, Keleş Muzaffer Oğuz, Kaya Cevdet, Güneş Mustafa, Öztürk Metin, Karaman Muhammet İhsan
Clinic of Urology, Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey.
Turk J Urol. 2014 Sep;40(3):134-7. doi: 10.5152/tud.2014.82195.
Benign prostate hyperplasia (BPH) is becoming more prevalent in parallel to the changing demographic structures of the community. Transurethral resection is still considered the most effective treatment. Due to advances in technology, different treatment modalities are being attempted. In our study, we compared the long-term results of standard transurethral resection of prostate (TURP) with plasmakinetic vaporization of prostate (PKVP, Gyrus Medical Ltd., Bucks, UK).
Of the 75 patients who were admitted to our outpatient clinic between 2001 and 2003 with lower urinary tract complaints and who were randomized into two groups (transurethral resection (TUR) and PKVP), 36 were enrolled to study and completed a follow-up period of 72 months.
Both groups were equal in terms of age and preoperative parameters. The preoperative maximum uroflow rate (Qmax) in the PKVP group was 6 (2.3) mL/s and the rates were 21.8 (3.4) and 20.1 (3.1) during the control visits at 36 and 72 months, respectively. For the PKVP group, these rates were 6 (3.1), 14.4 (2.6), and 15.6 (2.8), respectively. In terms of the international prostate symptom score (IPSS), for the TUR group, these values were 22 (3.8), 5.7 (1.2), and 7.9 (2.6). For the PKVP group, the respective values were 21 (3.4), 7.6 (1.4), and 11 (2.4). The IPSS and Qmax values measured at the 36(th) and 72(nd) months for both groups were significantly different from each other (p<0.05).
Compared to standard TURP, PKVP was found to be unsuccessful in the treatment of BPH when long-term outcomes were considered.
随着社区人口结构的变化,良性前列腺增生(BPH)正变得越来越普遍。经尿道切除术仍被认为是最有效的治疗方法。由于技术的进步,人们正在尝试不同的治疗方式。在我们的研究中,我们比较了标准经尿道前列腺切除术(TURP)与前列腺等离子体汽化术(PKVP,英国巴克斯郡吉勒斯医疗有限公司)的长期效果。
2001年至2003年间,75例因下尿路症状到我们门诊就诊的患者被随机分为两组(经尿道切除术(TUR)和PKVP),其中36例患者参与研究并完成了72个月的随访期。
两组在年龄和术前参数方面相当。PKVP组术前最大尿流率(Qmax)为6(2.3)毫升/秒,在36个月和72个月的对照访视期间,该值分别为21.8(3.4)和20.1(3.1)。对于PKVP组,这些值分别为6(3.1)、14.4(2.6)和15.6(2.8)。就国际前列腺症状评分(IPSS)而言,TUR组的这些值分别为22(3.8)、5.7(1.2)和7.9(2.6)。PKVP组的相应值分别为21(3.4)、7.6(1.4)和11(2.4)。两组在第36个月和第72个月测得的IPSS和Qmax值彼此有显著差异(p<0.05)。
从长期结果来看,与标准TURP相比,PKVP在治疗BPH方面未取得成功。