Mohan Harsh, Kundu Reetu, Dalal Usha
Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
Department of General Surgery, Government Medical College and Hospital, Chandigarh, India.
Turk J Urol. 2014 Sep;40(3):185-8. doi: 10.5152/tud.2014.93708.
Congenital anomalies of the kidney and urinary tract are common and include a wide anatomic spectrum. Duplex systems are one of the more common renal anomalies, with the majority being asymptomatic. Little is known about the molecular pathogenesis of these anomalies; however, certain causative genes have been implicated. The finding of renal cell carcinoma arising in a kidney with the duplication of pelvicalyceal system and ureters, as in the present case, is uncommon. The association between a duplex system and renal cell carcinoma may be more than a coincidence, requiring a deeper insight and further elucidation.
先天性肾和尿路异常很常见，包括广泛的解剖学范围。重复系统是较常见的肾脏异常之一，大多数情况下无症状。关于这些异常的分子发病机制知之甚少；然而，某些致病基因已被牵连。如本例中，在肾盂肾盏系统和输尿管重复的肾脏中发生肾细胞癌的情况并不常见。重复系统与肾细胞癌之间的关联可能不仅仅是巧合，需要更深入的研究和进一步阐明。
