Chen Kuo-Su, Chuang Cheng-Keng, Wu Ching-Herng, Liaw Chuang-Chi, Lee Ning
Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC.
Chang Gung Med J. 2003 May;26(5):377-82.
Despite the common anomaly of a duplicated collecting system in the urinary tract, urothelial cancer in a duplicated collecting system is a rare occurrence. Herein, we present 2 cases of renal pelvis tumor and 1 case of a ureter tumor which coexisted with a duplicated collecting system. One of the renal pelvis tumors developed bilateral transitional cell carcinoma within the bilateral duplicated pelvis. This has not been reported previously. The tumor of the ureter in the latter case was located at the junction site of the bifurcation. This finding is consistent with the postulation that urine reflux chronically irritates the distal segment of a duplicated ureter, rendering this segment susceptible to malignant change. Recurrence of the tumor is frequently observed, which necessitates an early diagnosis and radical treatment.
尽管尿路重复集合系统是一种常见的异常情况，但重复集合系统中发生尿路上皮癌却很少见。在此，我们报告2例肾盂肿瘤和1例输尿管肿瘤，它们均与重复集合系统并存。其中1例肾盂肿瘤在双侧重复肾盂内发生了双侧移行细胞癌。此前未见相关报道。后1例病例中输尿管肿瘤位于分叉的交界处。这一发现与以下推测一致，即尿液反流长期刺激重复输尿管的远端节段，使其易发生恶性改变。肿瘤复发很常见，因此需要早期诊断和根治性治疗。
