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单疗程穿刺抽吸与乙醇硬化治疗联合腹腔镜去顶术治疗有症状单纯性肾囊肿的比较。

Comparison of single-session aspiration and ethanol sclerotherapy with laparoscopic de-roofing in the management of symptomatic simple renal cysts.

作者信息

Efesoy Ozan, Tek Mesut, Bozlu Murat, Doruk Hasan Erdal

机构信息

Clinic of Urology, Toros State Hospital, Mersin, Turkey.

Department of Urology, Mersin University Faculty of Medicine, Mersin, Turkey.

出版信息

Turk J Urol. 2015 Mar;41(1):14-9. doi: 10.5152/tud.2015.77675.

Abstract

OBJECTIVE

The aim of the study was to compare the efficacy and cost-effectiveness of single-session aspiration and ethanol sclerotherapy with laparoscopic de-roofing in the management of symptomatic simple renal cysts.

MATERIAL AND METHODS

Between March 2010 and December 2012, patients with simple renal cysts presenting with pressure and pain symptoms were divided into two groups. In Group 1 following local anesthetic administration, single session percutaneous aspiration with 95% ethanol sclerotherapy (n=38) and in Group 2 transperitoneal laparoscopic de-roofing under general anesthesia (n=42) were performed. The data were evaluated retrospectively and demographic characteristics, duration of operation and hospitalization, complication rates, cost effectiveness, radiological and symptomatic success rates at six month- follow-up were compared between the two groups.

RESULTS

The mean age and gender of the patients, cyst diamater, side and localization of the cyst and indications for intervention were similar in two groups. The median course of treatment and hospitalization were signifcantly decreased in Group 1 (respectively 33 min versus 59 min and 6 hours versus 24 hours, p<0.001). As complications in Group 1 fever in two patients (5.3%) and in Group 2 bleeding requiring transfusion in one patient (2.4%) were observed (p=0.495). Total cost was calculated as $ 131.7 in Group 1 and $ 729.8 in Group 2. After the sixth month follow-up control radiological success rates were found to be signifcantly higher in Group 2, while symptomatic success rate is similar in both groups (63.2% versus 95.2%, p<0.001; 94.7% versus 97.6%, p=0.498, respectively).

CONCLUSION

Single-session percutaneous aspiration with alcohol sclerotherapy and laparoscopic de-roofing are safe and effective methods in the treatment of symptomatic simple renal cysts. While radiological recurrence rate was higher in single session percutaneous aspiration with alcohol sclerotherapy, however similar symptomatic recurrence rates were seen with laparoscopy. Therefore single session percutaneous aspiration combined with alcohol sclerotherapy seems to be an important option in the treatment of simple renal cysts when considering the duration of the operation, hospitalization and total costs of the process.

摘要

目的

本研究旨在比较单次穿刺抽吸联合乙醇硬化治疗与腹腔镜去顶术治疗有症状的单纯性肾囊肿的疗效和成本效益。

材料与方法

2010年3月至2012年12月期间,将出现压迫和疼痛症状的单纯性肾囊肿患者分为两组。第1组在局部麻醉后,进行单次经皮穿刺抽吸并注入95%乙醇硬化治疗(n = 38),第2组在全身麻醉下进行经腹腹腔镜去顶术(n = 42)。对数据进行回顾性评估,比较两组患者的人口统计学特征、手术时间和住院时间、并发症发生率、成本效益、随访6个月时的影像学成功率和症状缓解成功率。

结果

两组患者的平均年龄、性别、囊肿直径、囊肿部位和干预指征相似。第1组的中位治疗时间和住院时间显著缩短(分别为33分钟对59分钟和6小时对24小时,p < 0.001)。第1组有2例患者出现发热并发症(5.3%),第2组有1例患者出现出血需输血(2.4%)(p = 0.495)。第1组的总成本计算为131.7美元,第2组为729.8美元。随访6个月后,发现第2组的影像学成功率显著更高,而两组的症状缓解成功率相似(分别为63.2%对95.2%,p < 0.001;94.7%对97.6%,p = 0.498)。

结论

单次经皮穿刺抽吸联合乙醇硬化治疗和腹腔镜去顶术是治疗有症状的单纯性肾囊肿的安全有效方法。虽然单次经皮穿刺抽吸联合乙醇硬化治疗的影像学复发率较高,但腹腔镜手术的症状复发率相似。因此,考虑到手术时间、住院时间和整个过程的总成本,单次经皮穿刺抽吸联合乙醇硬化治疗似乎是治疗单纯性肾囊肿的一个重要选择。

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