Jones Theresa A, Adkins DeAnna L
Psychology Department, Neuroscience Institute, University of Texas at Austin, Austin, Texas; and
Neurosciences Department, and Health Sciences & Research Department, Colleges of Medicine & Health Professions, Medical University of South Carolina, Charleston, South Carolina.
Physiology (Bethesda). 2015 Sep;30(5):358-70. doi: 10.1152/physiol.00014.2015.
Stroke instigates regenerative responses that reorganize connectivity patterns among surviving neurons. The new connectivity patterns can be suboptimal for behavioral function. This review summarizes current knowledge on post-stroke motor system reorganization and emerging strategies for shaping it with manipulations of behavior and cortical activity to improve functional outcome.
中风会引发再生反应,从而重新组织存活神经元之间的连接模式。新的连接模式对于行为功能而言可能并非最优。本综述总结了目前关于中风后运动系统重组的知识,以及通过行为和皮层活动操纵来塑造该系统以改善功能结果的新兴策略。