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中风后运动系统重组:朝着完美状态进行刺激与训练

Motor System Reorganization After Stroke: Stimulating and Training Toward Perfection.

作者信息

Jones Theresa A, Adkins DeAnna L

机构信息

Psychology Department, Neuroscience Institute, University of Texas at Austin, Austin, Texas; and

Neurosciences Department, and Health Sciences & Research Department, Colleges of Medicine & Health Professions, Medical University of South Carolina, Charleston, South Carolina.

出版信息

Physiology (Bethesda). 2015 Sep;30(5):358-70. doi: 10.1152/physiol.00014.2015.

DOI:10.1152/physiol.00014.2015
PMID:26328881
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4556825/
Abstract

Stroke instigates regenerative responses that reorganize connectivity patterns among surviving neurons. The new connectivity patterns can be suboptimal for behavioral function. This review summarizes current knowledge on post-stroke motor system reorganization and emerging strategies for shaping it with manipulations of behavior and cortical activity to improve functional outcome.

摘要

中风会引发再生反应,从而重新组织存活神经元之间的连接模式。新的连接模式对于行为功能而言可能并非最优。本综述总结了目前关于中风后运动系统重组的知识,以及通过行为和皮层活动操纵来塑造该系统以改善功能结果的新兴策略。

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本文引用的文献

1
Transcranial direct current stimulation can enhance ability in motor imagery tasks.
Neuroreport. 2015 Aug 5;26(11):613-7. doi: 10.1097/WNR.0000000000000398.
2
Experience with the "good" limb induces aberrant synaptic plasticity in the perilesion cortex after stroke.健侧肢体的使用经历会在中风后损伤周围皮质诱发异常的突触可塑性。
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Inhibition of the contralesional hemisphere after stroke: reviewing a few of the building blocks with a focus on animal models.中风后对侧半球的抑制:以动物模型为重点回顾一些基础内容。
Prog Brain Res. 2015;218:361-87. doi: 10.1016/bs.pbr.2015.01.002. Epub 2015 Mar 30.
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Constraint-induced movement therapy after stroke.中风后的强制性运动疗法
Lancet Neurol. 2015 Feb;14(2):224-34. doi: 10.1016/S1474-4422(14)70160-7.
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A neuroanatomical framework for upper limb synergies after stroke.脑卒中后上肢协同作用的神经解剖学框架。
Front Hum Neurosci. 2015 Feb 16;9:82. doi: 10.3389/fnhum.2015.00082. eCollection 2015.
6
Epidural Electrical Stimulation for Stroke Rehabilitation: Results of the Prospective, Multicenter, Randomized, Single-Blinded Everest Trial.硬膜外电刺激用于中风康复:前瞻性、多中心、随机、单盲珠穆朗玛峰试验的结果
Neurorehabil Neural Repair. 2016 Feb;30(2):107-19. doi: 10.1177/1545968315575613. Epub 2015 Mar 6.
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Effects of extradural cortical stimulation on motor recovery in a rat model of subacute stroke.硬膜外皮质刺激对亚急性脑卒中大鼠模型运动恢复的影响。
Restor Neurol Neurosci. 2015;33(5):589-96. doi: 10.3233/RNN-140445.
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Enduring Poststroke Motor Functional Improvements by a Well-Timed Combination of Motor Rehabilitative Training and Cortical Stimulation in Rats.通过对大鼠进行适时的运动康复训练与皮层刺激相结合来实现中风后运动功能的持久改善。
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The global burden of hemorrhagic stroke: a summary of findings from the GBD 2010 study.出血性中风的全球负担:全球疾病负担研究2010的结果总结
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