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瓦里安边缘放射外科系统小射野剂量测定中使用的多个探测器的校正因子测量。

Correction factor measurements for multiple detectors used in small field dosimetry on the Varian Edge radiosurgery system.

作者信息

Tanny Sean, Sperling Nicholas, Parsai E Ishmael

机构信息

Department of Radiation Oncology, University of Toledo Medical Center, 1325 Conference Drive, Toledo, Ohio 43614.

出版信息

Med Phys. 2015 Sep;42(9):5370-6. doi: 10.1118/1.4928602.

Abstract

PURPOSE

Accurate dosimetry of small fields remains a challenge to the clinical physicist. Choosing the appropriate detector and determination of kQclin,Qmsr (fclin,fmsr) factors continue to be an area of active research. The purpose of this study is to evaluate the output factors for a dedicated stereotactic accelerator using multiple dosimeters designed for use in small fields and evaluate published kQclin,Qmsr (fclin,fmsr) factors relative to measured values using a commercial scintillating fiber.

METHODS

Four microionization chambers, a commercial plastic scintillation detector, and a semiconducting diode were used to measure output factors for a linear accelerator. Field sizes ranging from 6 × 6 to 0.6 × 0.6 cm(2) were measured in a water phantom at 10 cm depth for 100 cm SSD. All microionization chambers were mounted in both vertical and horizontal configurations. Fields were normalized to the output at 5 × 5 cm(2). Output correction factors, kQclin,Qmsr (fclin,fmsr), were calculated as the ratio of a detector response relative to the scintillating fiber response for a given clinical field size, fclin.

RESULTS

Ionization chambers consistently under-responded for small fields relative to the scintillating fiber. Variations in response between horizontal and vertical mounting were most notable for the microchambers, with the vertical mounting which reduced the magnitude of the necessary correction factor, kQclin,Qmsr (fclin,fmsr), for the microionization chambers ranging from 1.1 to 1.2 for the smallest field size at all energies. The semiconducting diode over-responded by 7% for the smallest field size across all energies, resulting in a kQclin,Qmsr (fclin,fmsr) of ∼ 0.93.

CONCLUSIONS

The commercial scintillating fiber, which produces accurate and consistent ratios of dose to water for nonstandard fields, can be used to measure correction factors for various detectors used in a clinical setting. This can allow for comparison of measured correction factors to previously published values.

摘要

目的

小射野的精确剂量测定对临床物理师而言仍是一项挑战。选择合适的探测器以及确定kQclin,Qmsr(fclin,fmsr)因子仍是活跃的研究领域。本研究的目的是使用多种专为小射野设计的剂量仪评估专用立体定向加速器的输出因子,并使用商用闪烁光纤评估已发表的kQclin,Qmsr(fclin,fmsr)因子相对于测量值的情况。

方法

使用四个微电离室、一个商用塑料闪烁探测器和一个半导体二极管来测量直线加速器的输出因子。在水模体中,于10 cm深度、100 cm源皮距下测量范围从6×6至0.6×0.6 cm²的射野尺寸。所有微电离室均以垂直和水平两种配置安装。射野以5×5 cm²处的输出进行归一化。输出校正因子kQclin,Qmsr(fclin,fmsr)计算为给定临床射野尺寸fclin下探测器响应与闪烁光纤响应的比值。

结果

相对于闪烁光纤,电离室对小射野的响应始终偏低。微电离室在水平和垂直安装时的响应差异最为显著,垂直安装可减小微电离室所需校正因子kQclin,Qmsr(fclin,fmsr)的幅度,在所有能量下最小射野尺寸时该因子范围为1.1至1.2。半导体二极管在所有能量下对最小射野尺寸的响应高估了7%,导致kQclin,Qmsr(fclin,fmsr)约为0.93。

结论

商用闪烁光纤可为非标准射野产生准确且一致的剂量与水的比值,可用于测量临床环境中使用的各种探测器的校正因子。这能够将测量的校正因子与先前发表的值进行比较。

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