[Morphological study of the damaged myocardium in autopsies with previous ECG and blood enzyme test evidence of various clinical forms of ischemic heart disease during exacerbation phase].

Of 98 patients who died from myocardial infarction as evidenced by sectional and histological examinations, during their life 74 had had signs of extensive myocardial infarction (EMI), 11 had presented with small myocardial infarction (SMI), 10, focal myocardial dystrophy (FMD), 3, angina pectoris (AP). In the acute period, the highest values of hyperenzymia, CPK, MB-CPK, ACT, LDH1, LDH2, and enzyme ratios were revealed in EMI, the lowest ones were seen in AP; SMI and FMD stood midway. A significant moderate direct relationship was established between the maximum activity of CPK, MB-CPK, and LDH1 and the histological sizes of ischemic necrosis as documented by planimetry. It was suggested that the topography and site of ischemic lesion determined life-time ECG evidence of respective clinical forms of coronary heart disease during its exacerbation, and the severity of hyperenzymia governed necrotic mass.