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Streptozotocin induced Alzheimer's disease like changes and the underlying neural degeneration and regeneration mechanism.

作者信息

Kamat Pradip Kumar

机构信息

Department of Anasthesiology, Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.

出版信息

Neural Regen Res. 2015 Jul;10(7):1050-2. doi: 10.4103/1673-5374.160076.

DOI:10.4103/1673-5374.160076
PMID:26330820
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4541228/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1068/4541228/cbcefc05c2bb/NRR-10-1050-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1068/4541228/73659a99d64a/NRR-10-1050-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1068/4541228/cbcefc05c2bb/NRR-10-1050-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1068/4541228/73659a99d64a/NRR-10-1050-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1068/4541228/cbcefc05c2bb/NRR-10-1050-g002.jpg

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Geniposide attenuates insulin-deficiency-induced acceleration of β-amyloidosis in an APP/PS1 transgenic model of Alzheimer's disease.栀子苷可减轻胰岛素缺乏诱导的阿尔茨海默病APP/PS1转基因模型中β-淀粉样变性的加速。
Neurochem Int. 2015 Oct;89:7-16. doi: 10.1016/j.neuint.2015.04.002. Epub 2015 Apr 13.
2
Mechanism of synapse redox stress in Okadaic acid (ICV) induced memory impairment: Role of NMDA receptor.冈田酸(脑室内注射)诱导记忆损伤中突触氧化还原应激的机制:N-甲基-D-天冬氨酸受体的作用
Neurochem Int. 2014 Oct;76:32-41. doi: 10.1016/j.neuint.2014.06.012. Epub 2014 Jun 28.
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Decreased insulin-like growth factor-I and its receptor expression in the hippocampus and somatosensory cortex of the aged mouse.
Murine Non-Transgenic Models of Alzheimer's Disease Pathology: Focus on Risk Factors.
阿尔茨海默病病理学的小鼠非转基因模型:关注风险因素。
Brain Sci. 2025 Mar 19;15(3):322. doi: 10.3390/brainsci15030322.
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Astaxanthin nanoemulsion improves cognitive function and synaptic integrity in Streptozotocin-induced Alzheimer's disease model.虾青素纳米乳剂改善链脲佐菌素诱导的阿尔茨海默病模型中的认知功能和突触完整性。
Metab Brain Dis. 2025 Mar 6;40(3):136. doi: 10.1007/s11011-025-01560-7.
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Impaired cerebral microvascular reactivity and endothelial SK channel activity in a streptozotocin-treated mouse model of Alzheimer's disease.链脲佐菌素处理的阿尔茨海默病小鼠模型中脑微血管反应性受损及内皮SK通道活性异常
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Front Pharmacol. 2024 Oct 31;15:1492237. doi: 10.3389/fphar.2024.1492237. eCollection 2024.
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Front Pharmacol. 2024 Jul 23;15:1395887. doi: 10.3389/fphar.2024.1395887. eCollection 2024.
10
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Sci Rep. 2024 Jul 8;14(1):15642. doi: 10.1038/s41598-024-66256-x.
老年小鼠海马体和体感皮层中胰岛素样生长因子-I及其受体表达降低。
Neurochem Res. 2014 Apr;39(4):770-6. doi: 10.1007/s11064-014-1269-3. Epub 2014 Mar 1.
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Pharmacol Biochem Behav. 2014 Feb;117:104-17. doi: 10.1016/j.pbb.2013.11.035. Epub 2013 Dec 10.
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Glucagon-like peptide-1 protects hippocampal neurons against advanced glycation end product-induced tau hyperphosphorylation.胰高血糖素样肽-1 可防止海马神经元受到晚期糖基化终产物诱导的 tau 过度磷酸化。
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Neuromolecular Med. 2013 Mar;15(1):102-14. doi: 10.1007/s12017-012-8199-5. Epub 2012 Sep 21.
10
A study on neuroinflammatory marker in brain areas of okadaic acid (ICV) induced memory impaired rats.一项关于冈田酸(ICV)诱导记忆障碍大鼠脑区神经炎症标志物的研究。
Life Sci. 2012 May 22;90(19-20):713-20. doi: 10.1016/j.lfs.2012.03.012. Epub 2012 Mar 26.