Jasty M, Bragdon C R, Schutzer S, Rubash H, Haire T, Harris W H
Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston 02114.
Scanning Microsc. 1989 Dec;3(4):1051-6; discussion 1056-7.
Bone ingrowth into titanium fiber mesh porous-surfaced canine total hip replacement prostheses was evaluated and quantified using a computer assisted image analysis system attached to a scanning electron microscope equipped with a back scattered electron detector. Excellent contrast between the bone, the porous metal and the soft tissues resulted in the backscatter mode, allowing easy differentiation of these components in real time by the image analysis based on gray scales. By three weeks the mean (+/- standard deviation) amount of bone ingrowth expressed as a percentage of porous layer measured 7.2% (+/- 1.5%) for the acetabular components, and 3.9% (+/- 1.7%) for the femoral components. At six weeks the amount of bone ingrowth increased to 10.5% (+/- 1.3%) for the acetabular components and 8.5% (+/- 1.4%) for the femoral components. Cementless prosthetic fixation using porous surfaced prostheses holds great promise in joint replacement surgery, and the ability to quantitate the amount of bone ingrowth will permit the evaluation of the efficacy of various techniques to improve bone ingrowth.
使用连接到配备背散射电子探测器的扫描电子显微镜的计算机辅助图像分析系统，对钛纤维网多孔表面犬全髋关节置换假体中的骨长入情况进行了评估和量化。在背散射模式下，骨、多孔金属和软组织之间形成了极佳的对比度，使得基于灰度的图像分析能够实时轻松区分这些成分。到三周时，以多孔层百分比表示的平均（±标准差）骨长入量，髋臼部件为7.2%（±1.5%），股骨部件为3.9%（±1.7%）。六周时，髋臼部件的骨长入量增加到10.5%（±1.3%），股骨部件增加到8.5%（±1.4%）。使用多孔表面假体的非骨水泥假体固定在关节置换手术中前景广阔，而量化骨长入量的能力将有助于评估各种改善骨长入技术的疗效。
