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[非骨水泥型髋臼多孔涂层的组织学研究。关于11例尸检取出的植入物]

[Histological study of the porous coating of the uncemented acetabulum. Apropos of 11 implants removed at autopsy].

作者信息

Pidhorz L E, Urban R M, Jacobs J J, Sumner D R, Galante J O

机构信息

Rush Presbyterian St Lukes Medical Center, Chicago, IL 60612.

出版信息

Chirurgie. 1993;119(6-7):334-9.

PMID:7805490
Abstract

Tissue ingrowth in the porous coating of 11 cementless acetabular components has been studied histologically. These cups were retrieved at autopsy from 8 patients who had undergone a primary total hip arthroplasty. Seven cups had a mean implantation period of 5.1 years, the other 4 had been in place for less than one year. This component was made of commercially pure (cp) titanium, with a porous surface of cp titanium fiber metal. The initial fixation of the cup was achieved by screws. The tissues of the porous coating were studied into 1 mm fields at four levels, and were categorized either as bone, marrow, cartilage or fibrous tissue. The fraction of void space within the porous coating occupied by bone was measured by backscattered scanning electron microscopy. The percentage of 1 mm fields with bony tissue was 20.9% and the fraction of void space occupied by bone was 12%. No regional significant difference was found. The number of fields with bone increased from the interface between the porous coating and the substrate of the cup to the interface between the outer surface of the porous coating and the host bone. All the screw threads were covered with lamellar bone. In the longest term cases, fine metallic and polyethylene debris were observed and their amount increased with time. This study showed that, despite the important variability in bone ingrowth, these cementless cups were able to give entire satisfaction to the patients.

摘要

对11个非骨水泥髋臼部件多孔涂层中的组织长入情况进行了组织学研究。这些髋臼杯是从8例行初次全髋关节置换术的患者尸检中取出的。7个髋臼杯的平均植入时间为5.1年,另外4个植入时间不到1年。该部件由商业纯钛(cp钛)制成,表面为cp钛纤维金属多孔结构。髋臼杯通过螺钉实现初始固定。在四个层面上,以1毫米为单位对多孔涂层组织进行研究,并将其分类为骨组织、骨髓组织、软骨组织或纤维组织。通过背散射扫描电子显微镜测量多孔涂层中被骨组织占据的孔隙空间比例。含有骨组织的1毫米区域的百分比为20.9%,被骨组织占据的孔隙空间比例为12%。未发现区域显著差异。从多孔涂层与髋臼杯基底的界面到多孔涂层外表面与宿主骨的界面,含有骨组织的区域数量增加。所有螺纹均被板层骨覆盖。在植入时间最长的病例中,观察到有细小的金属和聚乙烯碎片,且其数量随时间增加。本研究表明,尽管骨长入存在重要的变异性,但这些非骨水泥髋臼杯能够让患者完全满意。

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