Ronningen H, Lereim P, Galante J, Rostoker W, Turner T, Urban R
J Biomed Mater Res. 1983 Jul;17(4):643-53. doi: 10.1002/jbm.820170409.
A total hip surface replacement was performed on 13 adult mongrel dogs using a porous fiber metal composite for fixation to bone. Titanium fiber composite rings were molded onto cylindrical acetabular prostheses, and cobalt-chrome fiber inserts were sintered onto the cast cobalt-chrome femoral components. The animals were allowed unrestricted walking. Four dogs were sacrificed between 3 and 5 weeks, five at 7 weeks, one with a femoral neck fracture at 12 weeks, and three at 26 weeks. Bone ingrowth was accomplished in 20 of the 26 prosthetic components. This included 12 femoral components and eight acetabular. The main reason for failure appeared to be inadequate primary fixation, secondary to either poor design or technical difficulties experienced during the surgical procedure.
使用多孔纤维金属复合材料将其固定于骨,对13只成年杂种犬实施了全髋关节表面置换术。将钛纤维复合环模压到圆柱形髋臼假体上,将钴铬纤维植入物烧结到铸造的钴铬股骨部件上。允许动物自由行走。在3至5周之间处死4只犬,7周时处死5只,一只在12周时发生股骨颈骨折,26周时处死3只。26个假体部件中有20个实现了骨长入。其中包括12个股骨部件和8个髋臼部件。失败的主要原因似乎是初次固定不充分,这继发于设计不佳或手术过程中遇到的技术困难。