Nguyen Nicholas V, Burgos Arelis, Prok Lori
Department of Dermatology, School of Medicine, University of Colorado, Aurora, Colorado.
Department of Pediatrics, School of Medicine, University of Colorado, Aurora, Colorado.
Pediatr Dermatol. 2015 Nov-Dec;32(6):e296-7. doi: 10.1111/pde.12672. Epub 2015 Sep 4.
Trichodysplasia spinulosa is a rare folliculocentric polyomavirus infection observed in the setting of immunosuppression. We report a 7-year-old boy with pre-B-cell lymphoblastic leukemia who presented with folliculocentric spiny papules on the face. Histologic evaluation revealed hypertrophic bulbs, an expanded inner root sheath, and numerous brightly eosinophilic trichohyalin granules. We present this case to raise awareness of this rare but recognizable entity and to highlight the availability of appropriate diagnostic and therapeutic modalities.
棘状毛发发育异常是一种在免疫抑制情况下观察到的罕见的以毛囊为中心的多瘤病毒感染。我们报告一名7岁患前B细胞淋巴细胞白血病的男孩，其面部出现以毛囊为中心的棘状丘疹。组织学评估显示毛囊球部肥大、内根鞘扩张以及大量嗜酸性的毛透明蛋白颗粒。我们呈现此病例以提高对这种罕见但可识别疾病的认识，并强调合适的诊断和治疗方式的可用性。
