Gibbons Gary W
South Shore Hospital Center for Wound Healing , Weymouth, Massachusetts.
Adv Wound Care (New Rochelle). 2015 Sep 1;4(9):534-544. doi: 10.1089/wound.2015.0647.
To discuss the use of Grafix, a commercially available, cryopreserved placental membrane, for the treatment of chronic/stalled wounds of different etiologies. To describe the unique composition of Grafix, to provide an overview of the existing clinical evidence supporting the benefits of Grafix for wound treatment, and to share the experience of the South Shore Hospital Center for Wound Healing (Weymouth, MA) with Grafix for the treatment of nonhealing wounds. Clinical evidence supports the safety and efficacy of Grafix for the treatment of chronic/stalled wounds, including those that have failed other advanced treatment modalities. Grafix is a cryopreserved placental membrane manufactured utilizing a novel technology that enables the preservation of all placental membrane components in their native state. Placental membranes have a unique composition of extracellular matrix, growth factors, and cells (including mesenchymal stem cells), which makes this tissue unique among other advanced biological wound treatment modalities. Clinical evidences support the benefits of Grafix for head-to-toe wound treatment.
讨论使用Grafix（一种市售的冷冻保存胎盘膜）治疗不同病因的慢性/迁延不愈伤口。描述Grafix的独特成分，概述支持Grafix用于伤口治疗益处的现有临床证据，并分享南岸医院伤口愈合中心（马萨诸塞州韦茅斯）使用Grafix治疗不愈合伤口的经验。临床证据支持Grafix治疗慢性/迁延不愈伤口的安全性和有效性，包括那些对其他先进治疗方式无效的伤口。Grafix是一种利用新技术制造的冷冻保存胎盘膜，该技术能够将所有胎盘膜成分保持在其天然状态。胎盘膜具有细胞外基质、生长因子和细胞（包括间充质干细胞）的独特组成，这使得该组织在其他先进的生物伤口治疗方式中独一无二。临床证据支持Grafix对头至脚伤口治疗的益处。
