全人工心脏治疗的过去与现在：一个成功的故事
Past and Present of Total Artificial Heart Therapy: A Success Story.
作者信息
Samak Mostafa, Fatullayev Javid, Sabashnikov Anton, Zeriouh Mohamed, Rahmanian Parwis B, Choi Yeong-Hoon, Wippermann Jens, Wahlers Thorsten, Schmack Bastian, Ruhparwar Arjang, Dohmen Pascal M, Karck Matthias, Popov Aron-Frederik, Simon André R, Weymann Alexander
机构信息
Department of Cardiothoracic Surgery, Heart Center, University Hospital Cologne, Cologne, Germany.
Department of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
出版信息
Med Sci Monit Basic Res. 2015 Sep 7;21:183-90. doi: 10.12659/MSMBR.895418.
The totally artificial heart (TAH) is among the most prominent medical innovations of the 21st century, especially due to the increasing population with end-stage heart failure. The progressive course of the disease, its resistance to conventional therapy, and the scarcity of hearts available for transplantation were the prime impetus for developing a TAH, especially when other options of mechanical circulatory assist devices are exhausted. In this review, we narrate the history of TAH, give an overview of its technology, and address the pros and cons of the currently available TAH models in light of published clinical experience.
全人工心脏（TAH）是21世纪最杰出的医学创新之一，尤其是考虑到终末期心力衰竭患者人数的不断增加。疾病的进展过程、对传统治疗的抵抗性以及可用于移植的心脏的稀缺性是开发TAH的主要推动力，特别是当机械循环辅助装置的其他选择都已用尽时。在这篇综述中，我们讲述了TAH的历史，概述了其技术，并根据已发表的临床经验探讨了目前可用的TAH模型的优缺点。
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