[小鼠血液、骨髓和脾脏培养细胞中姐妹染色单体交换的频率]
[The frequency of sister chromatid exchanges in cultured cells of mouse blood, bone marrow and spleen].
作者信息
Chebotarev A N, Golovina M E
出版信息
Biull Eksp Biol Med. 1989 Dec;108(12):720-1.
PMID:2634449
Abstract
Analysis of factors leading to the increase of SCE in vitro is presented. Frequency of SCE is the same in the blood, spleen, marrow cell culture and does not influence upon the time of culture and BDU or BDC concentration. The authors consider that procedure preparation of the culture leads to an increase of SCE in vitro as compared to in vivo.
摘要
本文对导致体外姐妹染色单体交换（SCE）增加的因素进行了分析。血液、脾脏、骨髓细胞培养中的SCE频率相同，且不受培养时间以及溴脱氧尿苷（BDU）或溴脱氧胞苷（BDC）浓度的影响。作者认为，与体内情况相比，培养的操作准备会导致体外SCE增加。
Zotero 插件