Ipadeola A, Adeleye J O
Department of Medicine, University College Hospital, Ibadan, Nigeria.
Department of Medicine, College of Medicine, University of Ibadan, Nigeria.
Diabetes Metab Syndr. 2016 Jan-Mar;10(1):7-12. doi: 10.1016/j.dsx.2015.08.011. Epub 2015 Aug 22.
Persons with type 2 DM have a cardiovascular risk 2-4 times that of the normal population. Co-occurrence of metabolic syndrome (MS) with type 2 DM is associated with an increased risk of development of cardiovascular disease. The aim of this study was to determine the prevalence of the MS in patients with type 2 diabetes mellitus and to compare absolute cardiovascular risk in type 2 DM Patients with MS with those without MS.
Anthropometric measurements and Blood Pressure of 340 eligible patients with type 2 DM recruited into the study were taken. Participants' FPG, FLP and glycated haemoglobin were also estimated. Cardiovascular risk score was calculated using the United Kingdom Prospective Diabetes Study (UKPDS) risk engine. Diagnosis of the MS was the International Diabetes Federation Criteria (IDF).
Over 66% participants had MS. The absolute cardiovascular risk score was found to be similar in persons with type 2 DM whether they fulfilled the criteria for diagnosis metabolic syndrome or not.
The absolute cardiovascular risk score was similar in type 2 DM patients with or without the metabolic syndrome.
2型糖尿病患者的心血管疾病风险是正常人群的2至4倍。代谢综合征（MS）与2型糖尿病并存会增加心血管疾病发生的风险。本研究的目的是确定2型糖尿病患者中MS的患病率，并比较伴有MS和不伴有MS的2型糖尿病患者的绝对心血管疾病风险。
对纳入本研究的340例符合条件的2型糖尿病患者进行人体测量和血压测量。还对参与者的空腹血糖、空腹胰岛素和糖化血红蛋白进行了评估。使用英国前瞻性糖尿病研究（UKPDS）风险评估工具计算心血管疾病风险评分。采用国际糖尿病联盟标准（IDF）诊断MS。
超过66%的参与者患有MS。结果发现，无论是否符合代谢综合征的诊断标准，2型糖尿病患者的绝对心血管疾病风险评分相似。
伴有或不伴有代谢综合征的2型糖尿病患者的绝对心血管疾病风险评分相似。
