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The antioxidative properties of thiazolidine derivatives.

作者信息

Włodek L, Czubak J

机构信息

Institute of Medical Biochemistry, Copernicus Medical Academy, Kraków, Poland.

出版信息

Pol J Pharmacol Pharm. 1989 Jul-Aug;41(4):369-75.

PMID:2634830
Abstract

Antioxidative properties of thiazolidine compounds, adducts of L-cysteine with formaldehyde (thiazolidine-4-carboxylic acid), with pyruvate (2-methyl-thiazolidine-2,4-dicarboxylic acid), and glucose (2-/D-gluco-1',2',3',4',5'-penthahydroxypentyl/- thiazolidine-4-carboxylic acid) were studied. The investigated compounds, as well as L-cysteine and DL-penicillamine inhibited in vitro lipid peroxidation induced by NADPH, ethanol, and hydrogen peroxide in the suspension of rat liver microsomes.

摘要

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