You Jia-li, Zhu Yi-min
Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 May;44(3):344-8. doi: 10.3785/j.issn.1008-9292.2015.05.17.
Vertical transmission is the major route of HCV infection in children and draws much attention recently. With the development of assisted reproductive technology (ART), more and more HCV-serodiscordant infertile couples seek assisted reproduction treatment. Vertical transmission of HCV in ART cannot be avoided. Understanding the state of HCV infection of oocyte and embryo is helpful to solve the fertility problem and to control mother-to-child transmission.
垂直传播是儿童丙型肝炎病毒(HCV)感染的主要途径,近年来备受关注。随着辅助生殖技术(ART)的发展,越来越多HCV血清学不一致的不孕夫妇寻求辅助生殖治疗。ART中HCV的垂直传播无法避免。了解卵母细胞和胚胎的HCV感染状况有助于解决生育问题并控制母婴传播。