Isaacson A C, Huffman J E, Fried B
Int J Parasitol. 1989 Dec;19(8):943-4. doi: 10.1016/0020-7519(89)90124-0.
Laboratory hamsters (Mesocricetus auratus) were experimentally infected with 75 +/- 15 metacercarial cysts of Echinostoma caproni. Worms were recovered from days 7 to 89 post-infection with eight to 90 (average 37) parasites in the small intestine. Worm wet weights averaged 0.85 mg at 10 days, 1.8 mg at 17 days, 3.4 mg at 45 days, and 7.7 mg at 89 days; average dry weights for the identical days were, 0.15, 0.30, 0.70 and 2.2 mg, respectively. The average body area of worms fixed in hot (80 degrees C) alcohol-formalin-acetic acid was 0.21 mm2 on day 3, 4.9 mm2 on day 10, and 17.7 mm2 on day 42. Clinical signs in some hamsters included progressive unthriftiness and watery diarrhea. Gross examination revealed enlarged lymphatic nodules along the length of the small intestine. The histopathological responses of hamsters to the parasite showed erosion of the intestinal villi with lymphocytic infiltration being the primary response; hemorrhagic areas were also observed in the villi.
实验室仓鼠（金黄地鼠）被实验性感染75±15个卡氏棘口吸虫的囊蚴。在感染后第7天至89天从小肠中回收虫体，每条仓鼠有8至90条（平均37条）寄生虫。虫体湿重在感染后10天时平均为0.85毫克，17天时为1.8毫克，45天时为3.4毫克，89天时为7.7毫克；相同天数的平均干重分别为0.15毫克、0.30毫克、0.70毫克和2.2毫克。在热（80℃）酒精-福尔马林-乙酸中固定的虫体，其平均体表面积在第3天为0.21平方毫米，第10天为4.9平方毫米，第42天为17.7平方毫米。一些仓鼠的临床症状包括逐渐消瘦和水样腹泻。大体检查发现小肠全长的淋巴小结肿大。仓鼠对该寄生虫的组织病理学反应表现为肠绒毛糜烂，淋巴细胞浸润是主要反应；在绒毛中也观察到出血区域。
