Kim Hyeon-Ki, Konishi Masayuki, Takahashi Masaki, Tabata Hiroki, Endo Naoya, Numao Shigeharu, Lee Sun-Kyoung, Kim Young-Hak, Suzuki Katsuhiko, Sakamoto Shizuo
Graduate School of Sport Sciences, Waseda University, Saitama, Japan; Research Fellow of the Japan Society for the Promotion of Science, Tokyo, Japan.
Faculty of Sport Sciences, Waseda University, Saitama, Japan.
PLoS One. 2015 Sep 9;10(9):e0137567. doi: 10.1371/journal.pone.0137567. eCollection 2015.
To compare the effects of endurance exercise performed in the morning and evening on inflammatory cytokine responses in young men.
Fourteen healthy male participants aged 24.3 ± 0.8 years (mean ± standard error) performed endurance exercise in the morning (0900-1000 h) on one day and then in the evening (1700-1800 h) on another day with an interval of at least 1 week between each trial. In both the morning and evening trials, the participants walked for 60 minutes at approximately 60% of the maximal oxygen uptake (VO2max) on a treadmill. Blood samples were collected to determine hormones and inflammatory cytokines at pre-exercise, immediately post exercise, and 2 h post exercise.
Plasma interleukin (IL)-6 and adrenaline concentrations were significantly higher immediately after exercise in the evening trial than in the morning trial (P < 0.01, both). Serum free fatty acids concentrations were significantly higher in the evening trial than in the morning trial at 2 h after exercise (P < 0.05). Furthermore, a significant correlation was observed between the levels of IL-6 immediately post-exercise and free fatty acids 2 h post-exercise in the evening (r = 0.68, P < 0.01).
These findings suggest that the effect of acute endurance exercise in the evening enhances the plasma IL-6 and adrenaline concentrations compared to that in the morning. In addition, IL-6 was involved in increasing free fatty acids, suggesting that the evening is more effective for exercise-induced lipolysis compared with the morning.
比较年轻男性在早晨和晚上进行耐力运动对炎症细胞因子反应的影响。
14名年龄为24.3±0.8岁(平均值±标准误)的健康男性参与者,在一天的早晨(09:00 - 10:00)进行一次耐力运动,然后在至少间隔1周后的另一天晚上(17:00 - 18:00)进行耐力运动。在早晨和晚上的试验中,参与者均在跑步机上以大约最大摄氧量(VO2max)的60%步行60分钟。在运动前、运动后即刻以及运动后2小时采集血样以测定激素和炎症细胞因子。
与早晨试验相比,晚上试验运动后即刻血浆白细胞介素(IL)-6和肾上腺素浓度显著更高(两者均P < 0.01)。运动后2小时,晚上试验的血清游离脂肪酸浓度显著高于早晨试验(P < 0.05)。此外,晚上运动后即刻IL-6水平与运动后2小时游离脂肪酸水平之间存在显著相关性(r = 0.68,P < 0.01)。
这些发现表明,与早晨相比,晚上进行急性耐力运动可增强血浆IL-6和肾上腺素浓度。此外,IL-6参与了游离脂肪酸的增加,这表明与早晨相比,晚上在运动诱导的脂肪分解方面更有效。