套细胞淋巴瘤患者的局灶节段性肾小球硬化。
Focal segmental glomerulosclerosis in a patient with mantle cell lymphoma.
作者信息
Hindocha Sumeet, Gopaluni Seerapani, Collins Graham P, Shenbagaraman Packiam
机构信息
Oxford University Hospitals, Oxford, UK.
Royal Berkshire Hospital, Reading, UK.
出版信息
BMJ Case Rep. 2015 Sep 9;2015:bcr2015211765. doi: 10.1136/bcr-2015-211765.
Abstract
Mantle cell lymphoma (MCL) is a rare lymphoid neoplasm occurring in about 6% of all non-Hodgkin's lymphomas. Although nephrotic syndrome due to various glomerulopathies is well described in patients with lymphomas, focal segmental glomerulosclerosis (FSGS) with MCL has been reported only once before. We present a second case of FSGS associated with MCL that was resistant to standard treatment of FSGS but resolved when the underlying MCL was treated.
摘要
套细胞淋巴瘤（MCL）是一种罕见的淋巴样肿瘤，约占所有非霍奇金淋巴瘤的6%。尽管淋巴瘤患者中因各种肾小球病导致的肾病综合征已有详细描述，但MCL合并局灶节段性肾小球硬化（FSGS）此前仅报道过一例。我们报告了第二例与MCL相关的FSGS，该病例对FSGS的标准治疗耐药，但在潜在的MCL得到治疗后病情缓解。
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