Hirata T, Sekitani T, Okinaka Y, Matsuda Y
Department of Otolaryngology, Saiseikai Yamaguchi Hospital, Yamaguchi, Japan.
Acta Otolaryngol Suppl. 1989;468:371-3. doi: 10.3109/00016488909139079.
A serovirological study to clarify the pathogenesis of vestibular neuronitis was made on 44 patients. The diagnosis of vestibular neuronitis was made under the diagnostic criteria. Sera from all 44 cases were collected twice or more at defined intervals. Of these, 36 cases were treated as paired sera. Seventeen out of 36 paired cases showed significant change in serum viral antibody titer (HSV, 2 cases; CMV, 1 case; EBV, 7 cases; rubella, 2 cases; adeno., 2 cases; influ. A, 1 case; influ. B, 2 cases). It was assumed that infection caused by these detected viruses played an important role in the onset of vertigo in each case.
对44例患者进行了一项血清学研究,以阐明前庭神经炎的发病机制。前庭神经炎的诊断依据诊断标准进行。44例患者的血清均在规定间隔时间采集两次或更多次。其中,36例作为配对血清进行处理。36例配对病例中有17例血清病毒抗体滴度出现显著变化(单纯疱疹病毒,2例;巨细胞病毒,1例;EB病毒,7例;风疹病毒,2例;腺病毒,2例;甲型流感病毒,1例;乙型流感病毒,2例)。推测这些检测到的病毒引起的感染在每例眩晕发作中起重要作用。