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黎巴嫩托儿所中自闭症谱系障碍的患病率:一项横断面研究。

Prevalence of Autism Spectrum Disorder in Nurseries in Lebanon: A Cross Sectional Study.

作者信息

Chaaya Monique, Saab Dahlia, Maalouf Fadi T, Boustany Rose-Mary

机构信息

Department of Epidemiology and Population Health, American University of Beirut, Beirut, Lebanon.

Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, PO-box 11-0236, Riad El Solh Beirut, 1107 2020, Lebanon.

出版信息

J Autism Dev Disord. 2016 Feb;46(2):514-22. doi: 10.1007/s10803-015-2590-7.

Abstract

In Lebanon, no estimate for autism prevalence exists. This cross-sectional study examines the prevalence of Autism spectrum disorder (ASD) in toddlers in nurseries in Beirut and Mount-Lebanon. The final sample included 998 toddlers (16-48 months) from 177 nurseries. We sent parents the Modified Checklist for Autism in Toddlers (M-CHAT) for screening, and a self-administered questionnaire (associated factors). We imputed missing M-CHAT data with successful answers. Since there were no follow-up interviews for the M-CHAT, we used the positive predictive value (0.058) from a large study for prevalence estimates. ASD prevalence was 1 in 66 children (comparable to US). Ratios were: male/female: 1.05; Beirut/Mount-Lebanon: 1.2. Using a more representative sample and ascertaining results are needed for better prevalence estimates in Lebanon.

摘要

在黎巴嫩,尚无自闭症患病率的估计数据。这项横断面研究调查了贝鲁特和黎巴嫩山区托儿所中幼儿的自闭症谱系障碍(ASD)患病率。最终样本包括来自177家托儿所的998名幼儿(16至48个月)。我们向家长发放了《幼儿自闭症改良筛查量表》(M-CHAT)用于筛查,并发放了一份自填式问卷(相关因素)。我们用成功回答的数据填补了M-CHAT缺失的数据。由于没有对M-CHAT进行后续访谈,我们使用了一项大型研究中的阳性预测值(0.058)来进行患病率估计。ASD患病率为每66名儿童中有1例(与美国相当)。比例如下:男/女:1.05;贝鲁特/黎巴嫩山区:1.2。为了在黎巴嫩获得更准确的患病率估计,需要使用更具代表性的样本并确定结果。

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