孕中期羊水肌醇浓度与随后发生妊娠期糖尿病或妊娠高血压综合征的女性。
Second trimester amniotic fluid myo-inositol concentrations in women later developing gestational diabetes mellitus or pregnancy-induced hypertension.
作者信息
Santamaria Angelo, Corrado Francesco, Baviera Giovanni, Carlomagno Gianfranco, Unfer Vittorio, D'anna Rosario
机构信息
a Department of Pediatrics, Gynecology, Microbiology and Biomedical Sciences , University of Messina , Messina , Italy and.
b A. G. Un. Co. Obstetrics and Gynecology Center , Rome , Italy.
出版信息
J Matern Fetal Neonatal Med. 2016;29(14):2245-7. doi: 10.3109/14767058.2015.1081886. Epub 2015 Sep 12.
OBJECTIVE
To evaluate myo-inositol concentrations in amniotic fluid in women later developing gestational diabetes and hypertension.
METHODS
A retrospective study was carried out with three groups of amniotic fluid samples (15-18 gestational weeks): 30 gestational hypertension pregnancies, 30 gestational diabetes pregnancies, and 30 normal pregnancy.
RESULTS
A significant difference was observed in myo-inositol concentrations between the median gestational diabetes values (124.0 µmol/L, IQR 90.0-162.5) and the control group values (79.0 µmol/L, IQR 62.0-107.5), but also with gestational hypertension median values (79.0 µmol/L, IQR 67.75-92.0) (p < 0.001).
CONCLUSIONS
This study has shown that myo-inositol concentrations in amniotic fluid increased significantly in women later developing gestational diabetes compared to the control group.
目的
评估日后发生妊娠期糖尿病和高血压的女性羊水肌醇浓度。
方法
对三组羊水样本（孕15 - 18周）进行回顾性研究：30例妊娠期高血压妊娠、30例妊娠期糖尿病妊娠和30例正常妊娠。
结果
妊娠期糖尿病组中位数（124.0 µmol/L，四分位间距90.0 - 162.5）与对照组（79.0 µmol/L，四分位间距62.0 - 107.5）的肌醇浓度存在显著差异，与妊娠期高血压组中位数（79.0 µmol/L，四分位间距67.75 - 92.0）也有显著差异（p < 0.001）。
结论
本研究表明，与对照组相比，日后发生妊娠期糖尿病的女性羊水肌醇浓度显著升高。
Zotero 插件