Kunikullaya Kirthana Ubrangala, Goturu Jaisri, Muradi Vijayadas, Hukkeri Preethi Avinash, Kunnavil Radhika, Doreswamy Venkatesh, Prakash Vadagenahalli S, Murthy Nandagudi Srinivasa
Department of Physiology, M.S. Ramaiah Medical College and teaching hospitals, MSR Nagar, MSRIT Post, Bangalore, Karnataka, India.
Department of Physiology, M.S. Ramaiah Medical College and teaching hospitals, MSR Nagar, MSRIT Post, Bangalore, Karnataka, India.
Complement Ther Med. 2015 Oct;23(5):733-40. doi: 10.1016/j.ctim.2015.08.003. Epub 2015 Aug 5.
Ragas of Indian music are said to be beneficial in normalizing blood pressure (BP). The objective of this study was to evaluate the effect of passive listening to relaxing raga on the autonomic functions of hypertensives and prehypertensives and provide scientific evidence.
Ethical clearance was obtained from the institutional review board. A prospective, randomized controlled trial was done on hundred prehypertensives/stage I hypertensives, randomly divided into two groups (n=50 in each). Group 1 received music intervention along with lifestyle modifications while Group 2 received only lifestyle modifications (according to Joint national committee VII guidelines). Group 1 listened to raga bhimpalas played on flute for 15min daily for at least 5 days/week for 3 months. The main outcome measures were heart rate variability (HRV) (Power lab 15T, AD Instruments), BP and stress levels (State Trait anxiety inventory score). All HRV variables were log transformed for analysis. Statistical analysis was done using SPSS version 18.0 with P<0.05 being considered statistically significant.
Group 1 exhibited significant reduction in stress levels, diastolic BP and systolic BP decreased in Group 2 after intervention. Insignificant rise in parasympathetic parameters of HRV (SDNN, RMSSD, HF ms(2), HF nu) was seen after intervention in both the groups. We found significantly increased parasympathetic and lower sympathetic parameters (LF ms(2), LF nu, LF/HF) in Group 1 and 2 males and females of Group 2. The results suggest that females of Group 1 were least compliant with the given intervention.
Passive listening to Indian music along with conventional lifestyle modifications has a role in normalizing BP through autonomic function modification and thus can be used as a complementary therapy along with other lifestyle modifications.
据说印度音乐的拉格对血压正常化有益。本研究的目的是评估被动聆听舒缓的拉格对高血压患者和高血压前期患者自主神经功能的影响,并提供科学依据。
获得了机构审查委员会的伦理批准。对100名高血压前期/Ⅰ期高血压患者进行了一项前瞻性随机对照试验,随机分为两组(每组n = 50)。第1组在进行生活方式改变的同时接受音乐干预,而第2组仅接受生活方式改变(根据美国国家联合委员会第七版指南)。第1组每天听长笛演奏的拉格·宾帕拉斯15分钟,每周至少5天,持续3个月。主要观察指标为心率变异性(HRV)(Powerlab 15T,AD Instruments)、血压和压力水平(状态特质焦虑量表评分)。所有HRV变量均进行对数转换以进行分析。使用SPSS 18.0版进行统计分析,P<0.05被认为具有统计学意义。
干预后,第1组的压力水平显著降低,第2组的舒张压和收缩压下降。两组干预后HRV的副交感神经参数(SDNN、RMSSD、HF ms²、HF nu)均有不显著升高。我们发现第1组的副交感神经参数显著增加,第2组的交感神经参数(LF ms²、LF nu、LF/HF)较低,第1组的男性和女性以及第2组的女性均如此。结果表明,第1组的女性对给定干预的依从性最差。
被动聆听印度音乐并结合传统生活方式改变,通过自主神经功能调节对血压正常化有作用,因此可作为其他生活方式改变的辅助治疗方法。