Kunikullaya Kirthana Ubrangala, Goturu Jaisri, Muradi Vijayadas, Hukkeri Preethi Avinash, Kunnavil Radhika, Doreswamy Venkatesh, Prakash Vadagenahalli S, Murthy Nandagudi Srinivasa
Department of Physiology, M S Ramaiah Medical College and Group of Hospitals, Bangalore, Karnataka, India.
Department of Physiology, M S Ramaiah Medical College and Group of Hospitals, Bangalore, Karnataka, India.
Complement Ther Clin Pract. 2016 May;23:102-9. doi: 10.1016/j.ctcp.2015.05.004. Epub 2015 May 12.
To evaluate the change in blood pressure (BP) after 3 months of music intervention combined with lifestyle modifications, in comparison with conventional lifestyle modifications.
A Prospective randomized control trial was conducted on hundred prehypertensives or stage I hypertensives who were randomly divided into two groups (n = 50 each). Both the groups were given lifestyle modifications while one had added music intervention (raga bhimpalas) for 3 months. Main outcome measures were 24 h ambulatory BP monitoring, stress levels, and biomarkers of hypertension.
Mean (SD) of diastolic BP (DBP) pre and post intervention were overall = 85.1(6.8) and 83(8.7){P = 0.004}, awake = 87.7(7.6) and 85.9(9.2){P = 0.021}. Regression analysis showed association between diastolic BP change and post-intervention stress score in the music intervention group. Significant change in BP was seen among those who were prehypertensives prior to intervention.
Music decreased DBP and when used as an adjunct benefitted subjects with initial BP in prehypertension range.
评估音乐干预联合生活方式改变3个月后血压(BP)的变化,并与传统生活方式改变进行比较。
对100名高血压前期患者或I期高血压患者进行前瞻性随机对照试验,将他们随机分为两组(每组n = 50)。两组均进行生活方式改变,其中一组额外进行3个月的音乐干预(raga bhimpalas)。主要结局指标为24小时动态血压监测、压力水平和高血压生物标志物。
干预前后舒张压(DBP)的均值(标准差)总体分别为85.1(6.8)和83(8.7){P = 0.004},清醒时分别为87.7(7.6)和85.9(9.2){P = 0.021}。回归分析显示音乐干预组中舒张压变化与干预后压力评分之间存在关联。干预前为高血压前期的患者血压出现显著变化。
音乐可降低舒张压,作为辅助手段对初始血压处于高血压前期范围的受试者有益。